Results 191 to 200 of about 732,173 (296)

Enhanced Endoscopic Internal Drainage of Gastric Abscess Through Additively Manufactured Stents

Advanced Healthcare Materials, EarlyView.
Postoperative gastric leaks are often treated with off‐label biliary double‐pigtail stents, yet conventional extruded designs are not optimized for leak anatomy, can migrate, and may limit abscess evacuation. PETALS is introduced to optimize transmural drainage geometry and enable patient‐specific 3D‐printable stents.
Parima Phowarasoontorn, Yongbin Ko, Juan S. Barajas‐Gamboa, Juan P. Pantoja, Oraib Al‐Ketan, Mohamed Ali, Sungyun Sohn, Heba Tageldeen Naser, Abdel‐Hameed Dabbour, Batoul Khlaifat, Ahmed AlZubaidi, Carlos Abril Vega, John Rodriguez, Matthew Kroh, Khalil B. Ramadi   +14 more
wiley   +1 more source

Integration of Transcriptomics and WGCNA to Characterize Trichoderma harzianum-Induced Systemic Resistance in Astragalus mongholicus for Defense against Fusarium solani. [PDF]

Genes (Basel)
Niu J, Yan X, Bai Y, Li W, Lu G, Wang Y, Liu H, Shi Z, Liang J.   +8 more
europepmc   +1 more source

Reconstruction of a gene regulatory network of the induced systemic resistance defense response in Arabidopsis using boolean networks. [PDF]

BMC Bioinformatics, 2020
Timmermann T, González B, Ruz GA.
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Root Colonization by Trichoderma atroviride Triggers Induced Systemic Resistance Primarily Independent of the Chitin-mediated Signaling Pathway in Arabidopsis. [PDF]

Microbes Environ
Sakai A, Yamagata H, Naito K, Yoshioka M, Tominaga T, Ifuku S, Kaminaka H.   +6 more
europepmc   +1 more source

Mechanisms of rhizobacteria-mediated induced systemic resistance

, 2001
Some of non-pathogenic rhizosphere bacteria reduce disease by activating a resistance mechanism in the plant called rhizobacteria-mediated induced systemic resistance (ISR). Rhizobacteria-mediated ISR resembles classic pathogen-induced systemic acquired resistance (SAR) in that both types of induced resistance render uninfected plant parts more ...
Hase, S., Pieterse, C.M.J., van Loon, L.C.   +2 more
openaire   +3 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Plant‐Produced Viral Nanoparticles Decorated with Nanobodies Against HER2 Improve Retention and Recruitment of Immune Cells in Solid Tumors

Advanced Healthcare Materials, EarlyView.
Potato virus X is a filamentous RNA plant virus that can be engineered into a molecular tool for cancer therapy. We produced genetically‐encoded virus‐derived nanoparticles decorated with nanobodies targeting cancer cell receptors, epidermal growth factor receptor (EGFR) and human epidermal growth factor 2 (HER2).
Enrique Lozano‐Sanchez, Miguel A. Moreno‐Gonzalez, Fernando Merwaiss, Nicole F. Steinmetz, José‐Antonio Daròs   +4 more
wiley   +1 more source

Trichoderma virens colonization of maize roots triggers rapid accumulation of 12-oxophytodienoate and two ᵧ-ketols in leaves as priming agents of induced systemic resistance. [PDF]

Plant Signal Behav, 2020
Wang KD, Gorman Z, Huang PC, Kenerley CM, Kolomiets MV.   +4 more
europepmc   +1 more source