Results 251 to 260 of about 732,173 (296)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Editorial: Combination of photodynamic therapy and immunotherapy to overcome cancer resistance. [PDF]

Front Immunol
Hoseini-Ghahfarokhi M, Olofinsan KA, Sarbadhikary P, Kah G, Mulaudzi PE, Moloudi K.   +5 more
europepmc   +1 more source

Intermittent Fasting and Androgen Receptor Signaling in Prostate Cancer: Metabolic Crosstalk and Therapeutic Implications. [PDF]

Int J Mol Sci
Gromadzka G, Bendykowska M.
europepmc   +1 more source

Induced systemic resistance and the rhizosphere microbiome

Plant Pathology Journal , 2012
Bakker, P.A.H.M., Berendsen, R.L., Pieterse, C.M.J.   +2 more
openaire   +2 more sources

Antigen-Presenting Cell Isolevuglandins Link Salt Sensitivity of Blood Pressure to Insulin Resistance.

J Clin Endocrinol Metab
Ertuglu LA, Demirci M, Mutchler AL, Laffer CL, Saleem M, Ikizler TA, Kirabo A.   +6 more
europepmc   +1 more source

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Systemic Acquired Resistance and Induced Systemic Resistance in Conventional Agriculture

Crop Science, 2004
Plants possess a range of defenses that can be actively expressed in response to pathogens and parasites of various scales, ranging from microscopic viruses to insect herbivores. The timing of these defense responses is critical and can be the difference between being able to cope or succumbing to the challenge of a pathogen or parasite.
Gary E. Vallad, Robert M. Goodman
openaire   +1 more source

Pathogen-induced systemic resistance in Ipomoea purpurea

Oecologia, 1995
Infection of Ipomoea purpurea by anthracnose, the disease caused by the fungal pathogen Colletotrichum dematium, increases resistance to subsequent infections on previously uninfected leaves. Fungal isolates varied in their levels of virulence but not in the extent to which they induced resistance.
Ellen L, Simms, Todd J, Vision
openaire   +2 more sources

Systemic Induced Resistance

2000
Induced resistance is the phenomenon in which a plant, once appropriately stimulated, exhibits an enhanced resistance upon “challenge” inoculation with a pathogen. Induced resistance can be localized as well as systemic, and can be induced by limited pathogen infection, avirulent pathogens, certain non-pathogenic bacteria, and certain chemicals ...
openaire   +2 more sources

Induced Systemic Resistance in Plants

1991
Those investigating plant immune systems are faced with a dilemma. Disease resistance/ susceptibility in plants exhibit a high degree of specificity at many levels; however, specific mechanisms for eliciting resistance and specific mechanisms for disease resistance have not been established.
Nageswara Rao Madamanchi, Joseph Kuć
openaire   +1 more source