Results 241 to 250 of about 184,660 (305)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Evidence of Rapid Evolution in Herbivory Defense Responses With Conserved Trade-Offs in Populations of <i>Medicago polymorpha</i>. [PDF]

Ecol Evol
Rowe SL, Lopez ZC, Ross D, Sackos C, Porter SS, Friesen ML, Jack CN.   +6 more
europepmc   +1 more source

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

Advanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich, Noah S. David, Markus J. Buehler   +2 more
wiley   +1 more source

Targeted immune response gene expression profiles linked with necrosis and mortality in preterm infants with surgical necrotizing enterocolitis. [PDF]

World J Pediatr Surg
Garg PM, Riddick R, Zhang P, Shenberger J, Varshney N, Sawaya D, Garg P.   +6 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Exonuclease ISG20 inhibits human cytomegalovirus replication by inducing an innate immune defense signature. [PDF]

PLoS Pathog
Hehl M, Scherer M, Stegmann C, Raubuch EM, Ploil C, Rummel T, Kirchner P, Kottmann N, Reichel A, Kuderna AK, König AC, Friedel CC, Erhard F, Stamminger T.   +13 more
europepmc   +1 more source

Salicylic acid induces cultivar specific compromises in yield, fruit quality and defense metabolism of heat stressed strawberry. [PDF]

Sci Rep
Khajeh Sorkhoeih M, Hamidi Moghaddam A, Seyedi A.   +2 more
europepmc   +1 more source

Tomato secondary metabolites as natural regulators of <i>Bemisia tabaci</i> behavior and performance: current applicability and prospects. [PDF]

Front Plant Sci
Maldonado Machado da Cruz VH, Rutz da Silva T, Gimenez Cremonez P, Biscaia Ribeiro da Silva AL, Vergilio Visentainer J, Rodrigues C.   +5 more
europepmc   +1 more source

Prophage-encoded RexAB-type phage defense system in Pseudomonas putida. [PDF]

Sci Rep
Rosendahl S, Kängsep A, Ainelo A, Lipu A, Tamman H, Hõrak R.   +5 more
europepmc   +1 more source