Results 141 to 150 of about 158,217 (287)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Technical-parameter calculation model for underground low-power electrical lines and indoor installations used in telecommunications

Ingeniería e Investigación, 2011
This article presents an analysis of electrical distribution theory for 60Hz-lines operating at low voltage, particularly underground lines and residential indoor installations. Such distribution lines’ behaviour is observed as a function of frequency to
Henry Bastidas Mora, Marlon Patiño Bernal, Gilma Inés Ángel Castillo   +2 more
doaj  

Models for a Fast Computation of Internal Overvoltages in Medium-Frequency Transformers

IEEE Open Journal of Power Electronics
The fast switching of wide-bandgap (WBG) devices and the resulting harmonics in the switching waveforms can cause significant overvoltages in medium frequency transformers (MFTs).
Bastian Korthauer, Jurgen Biela
doaj   +1 more source

Microbian control associated with resistance inductors for Diaphorina citri Kuwayama, 1908 (HEMIPTERA: LIVIIDAE)

, 2023
Éder Málaga Carrilho
openalex   +1 more source

ESTIMATION OF MAXIMUM AND MINIMUM INDUCTANCE OF 6/4 SWITCHED RELUCTANCE MACHINE [PDF]

, 2013
Hassan M. Mahmoud, M. El-Shamoty, A. S. Farahat, Mohammed El-Sersawi   +3 more
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Non-Axisymmetric Tokamak Plasma Equilibrium by 3-D Multi-Layers Method

Applied Sciences
A three-dimensional (3-D) Multi-Layers Method (MLM) of an extension of the axisymmetric version has been developed to compute non-axisymmetric tokamak plasma equilibria with a separatrix.
Jingting Wang, Hiroaki Tsutsui
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Class of high boost inverters based on switched‐inductor structure [PDF]

, 2015
Minh‐Khai Nguyen, Tuan‐Vu Le, Sung‐Jun Park, Young‐Cheol Lim, Jiyoon Yoo   +4 more
openalex   +1 more source

Reduced-order modelling of switched/inductor- capacitor based high gain converter for fuel cell application

, 2022

openalex   +1 more source