Results 101 to 110 of about 2,511,435 (296)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Quotient inductive-inductive definitions [PDF]

open access: yes, 2017
In this thesis we present a theory of quotient inductive-inductive definitions, which are inductive-inductive definitions extended with constructors for equations. The resulting theory is an improvement over previous treatments of inductive-inductive and indexed inductive definitions in that it unifies and generalises these into a single framework. The
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Od Bacona do Hume’a – istota i odcienie empiryzmu w nowożytnej Anglii

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2012
The aim of the article is to give a brief overview of English empiricism, particularly in modern philosophy. The paper will firstly examine the pre-enlightenment thought of F. Bacon, upon which it will discuss the empiricism of J. Locke, G.
Bolesław Andrzejewski
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Reed Switch Overcurrent Protection: New Approach to Design

open access: yesEnergies
The problem of getting rid of expensive and metal-intensive current transformers has been declared by CIGRE as strategically important for the electric power industry. However, almost all traditional current protections receive information from measuring
Dauren Dzhambulovich Issabekov   +4 more
doaj   +1 more source

Ny i undervisning i høyere utdanning - Hvordan universitetslærere har erfart å bli tatt imot og fulgt opp som nyansatte

open access: yesUniped, 2016
Artikkelen fokuserer på hvordan universitetslærere ved to norske universiteter har erfart mottaket, introduksjonen og oppfølgingen de fikk som nyansatte. Studien viser at universitetene har utviklet gode sentrale opplegg for introduksjon og veiledning av
Carl Cato Wadel, Eilef Johan Gard
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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