Results 241 to 250 of about 4,122,199 (286)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Comparing three induction regimens for nasopharyngeal carcinoma: a propensity score-matched analysis. [PDF]

Ther Adv Med Oncol
Dai J, Pan Y, Liu Y, Pan Y, Wang D, Liang Y, Wei Y, Chen H, Zhang B, Wu X, Liu B, Kong X, Mo Y, Ruan X, Liao S, Lin X, Huang C, Xu J, Mo F, Jiang W.   +19 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

High-Throughput Screen of NPQ in Sorghum Shows Highly Polygenic Architecture of Photoprotection. [PDF]

Plant Environ Interact
Vath RL, Fernandes SB, Monier B, Głowacka K, Walter J, Lipka AE, Ferguson J, Bernacchi CJ, Pederson T, Kromdijk J.   +9 more
europepmc   +1 more source

Misoprostol combined with artificial membrane stripping showed the best effect of induction among women with gestational diabetes mellitus: a retrospective cohort study. [PDF]

Rev Assoc Med Bras (1992)
Li X, Yang Q, Zhang X, He L, Wu J.
europepmc   +1 more source

IFN-λ4 Exhibits Differential Induction and Antiviral Activity in RSV and HMPV Infections. [PDF]

Viruses
Martínez-Espinoza I, Babawale PI, Guerrero-Plata A.   +2 more
europepmc   +1 more source

Transient inhibition of MEK/ERK and WNT pathways enhances direct differentiation of primed hPSCs into functional trophoblast stem cells. [PDF]

Cell Regen
Jiang Q, Liu P, Chen C.
europepmc   +1 more source

Impact of a GABA-Producing <i>Lactococcus lactis</i> on Microbiota and Mycobiota During CNS Inflammatory Demyelination. [PDF]

FASEB Bioadv
Hill K, LaFollette A, Kirby TO, Negrete S, Babcock D, Felton K, Kohl H, Sharma K, Castillo A, Roullet JB, Gibson KM, Ochoa-Repáraz J.   +11 more
europepmc   +1 more source

Inductive Logic

, 2012
openaire   +2 more sources