Results 121 to 130 of about 1,332,541 (298)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Demo 20-21 Induction Coil

, 2001
An induction coil arrangement is demonstrated using the apparatus of Figure 1. The primary coil is powered by a DC power supply, and turned on and off by a magnetic make-and-break switch. The changing field in the secondary coil induces a large voltage

core  

Induction treatments with and without addition of one dose anthracycline to all-trans retinoid acid and arsenic in pediatric non-high-risk acute promyelocytic leukemia: study protocol for a randomized controlled trial

Trials
Background The treatment of all-trans retinoic acid (ATRA) and arsenical agent has revolutionarily improved the prognosis of acute promyelocytic leukemia (APL) both in adults and children.
Zhong Fan, Xiu-Ya Huang, Dan-Ping Huang, Jie-Si Luo, Jia-Yin Su, Xiao-Li Zhang, Yu Li, Li-Na Wang, Cong Liang, Xue-Qun Luo, Li-Bin Huang, Yan-Lai Tang   +11 more
doaj   +1 more source

Nimotuzumab Combined with Induction Chemotherapy and Concurrent Chemoradiotherapy in Unresectable Locally Advanced Hypopharyngeal Carcinoma: A Single Institution Experience in China

Cancer Management and Research, 2020
Xin Tian, Ying Xuan, Rong Wu, Song Gao Department of Clinical Oncology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, People’s Republic of ChinaCorrespondence: Song GaoDepartment of Clinical Oncology, Shengjing Hospital
Tian X, Xuan Y, Wu R, Gao S
doaj  

Neoadjuvant immunotherapy: is this the “new” induction chemotherapy? [PDF]

British Journal of Oral and Maxillofacial Surgery, 2019
Kanatas, AN, Doumas, S
openaire   +3 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The impact of the interval between the induction of chemotherapy and radiotherapy on the survival of patients with nasopharyngeal carcinoma

, 2019
Shiping Yang,1,2,* Xiaoling Fu,3,* Guang Huang,2 Junni Chen,2 Shishi Luo,4 Zhenping Wang,4 Fanzhong Kong,2 Gang Wu,2 Shaomin Lin,2 Fen Wang,2 Longhua Chen1 1Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou ...
Lin S, Chen J, Fu X, Huang G, Chen L, Kong F, Wang F, Luo S, Wu G, Yang S, Wang Z   +10 more
core  

Induction Chemotherapy: A Surgeonʼs Perspective [PDF]

Journal of Thoracic Oncology, 2006
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source