Results 151 to 160 of about 247,637 (262)

Safety and efficacy of combining midostaurin and gemtuzumab ozogamicin with induction chemotherapy in FLT3-mutated AML. [PDF]

Blood Adv
Russell N, Othman J, Cumming O, Thomas A, Tedjaseputra A, Potter N, Jovanovic J, Gilkes A, Batten L, Canham J, Hinson E, Runglall M, Aucken P, Kottaridis P, Cavenagh J, Arnold C, Freeman S, Dennis M, Knapper S, Dillon R.   +19 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Efficacy, safety, and survival outcomes of radiotherapy combined with nimotuzumab following induction chemotherapy in locally advanced head and neck cancer. [PDF]

Front Oncol
Zhuang Y, Chen C, Xu Z, Lin K.
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Effect of afatinib combined with induction chemotherapy on primary tumor regression and safety of surgical margins in locally advanced oral cancer. [PDF]

Am J Transl Res
Sun J, Huang Y, Wang Y, Zhao Q.
europepmc   +1 more source

Induction chemotherapy for acute leukemia

Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 1981
openaire   +4 more sources

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Induction chemotherapy in recurrent, unresectable esthesioneuroblastoma

Cancer Research, Statistics, and Treatment, 2018
Sachin Dhumal, Nilesh Sable, Vijay M Patil, Dilip Harindran Vallathol, Kumar Prabhash   +4 more
doaj   +1 more source

Gram-negative blood-stream infections and emerging antimicrobial resistance in children with acute myeloid leukemia during induction chemotherapy at Children's Cancer Hospital Egypt 57357. [PDF]

Front Oncol
Mbatia G, Khedr R, Lehmann L, Anany ME, Alsheshtawi K, Hassanain O, Ahmed S, Hassanain O, Shalaby L, Elhaddad A.   +9 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source