Results 251 to 260 of about 262,962 (308)

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Evaluation of Nutritional Status During Induction Chemotherapy in Patients With Acute Leukemia. [PDF]

Cureus
Thomas S, Mahapatra M, Seth T, Viveka J.
europepmc   +1 more source

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx. [PDF]

Head Neck
Risch Z, Bellile E, Bughrara MS, Swiecicki PL, Casper K, Malloy K, Hogikyan N, Spector M, Shuman A, Stucken C, Chinn S, Chepeha DC, Jolly S, Mierzwa M, Bradford C, Eisbruch A, Carey T, Prince M, Wolf GT, Worden FP.   +19 more
europepmc   +1 more source

Final survival analysis of induction chemotherapy with lobaplatin and fluorouracil versus cisplatin and fluorouracil followed by concurrent chemoradiotherapy in nasopharyngeal carcinoma: a multicenter, randomized, phase 3 trial. [PDF]

Nat Commun
Cao X, Zhou JY, Huang HY, Guo L, Huang YY, Qiu WZ, Lin ZC, Cao KJ, Mo HY, Li XM, Li ZH, Han F, He YX, Liu YM, Bai YR, Wu SX, Ke LR, Chen X, Liang CX, Luo ZY, Xia Y, Deng Y, Miao JJ, Xia WX, Liang H, Zhao C, Xiang YQ, Guo X, Lv X.   +28 more
europepmc   +1 more source

Predictive performance of MRI and CT radiomics in predicting the response to induction chemotherapy in nasopharyngeal carcinoma: a network meta-analysis. [PDF]

Front Oncol
Jian Y, Peng J, Yang G, He X, Wang J, Yin J, Shi H, Tao D, Lan Q, Yang Z, Shu Z.   +10 more
europepmc   +1 more source

Comprehensive geriatric assessment (CGA) scale does not effectively identify elderly AML patients suitable for intensive induction chemotherapy - a multicenter study from Polish Adult Leukemia Group. [PDF]

Ann Hematol
Budziszewska BK, Łomiak M, Barankiewicz J, Patkowska E, Helbig G, Bołkun Ł, Irga-Staniukiewicz A, Kiżewska A, Piekarska A, Koclęga A, Pluta A, Kuydowicz M, Kościołek-Zgódka S, Cichocka E, Malenda A, Wójcik K, Gromek T, Małecki P, Grosicki S, Giebel S, Wierzbowska A, Lech-Marańda E.   +21 more
europepmc   +1 more source

Induction Chemotherapy

, 2011
Induction chemotherapy, as part of an integrated plan of management for locally advanced cancers, is being practised throughout the world in independent, isolated departments in universities, teaching hospitals, and clinical schools. Frequently, however,
Gay, B., Matter, M., Christinat, A., Zouhair, A., Leyvraz, S.   +4 more
openaire   +2 more sources

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Induction of Apoptosis by Cancer Chemotherapy

Experimental Cell Research, 2000
Studies performed over the past five years have demonstrated that there are two major cell-intrinsic pathways for inducing apoptosis, one that begins with ligation of cell surface death receptors and another that involves mitochondrial release of cytochrome c.
S H, Kaufmann, W C, Earnshaw
openaire   +2 more sources