This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source
Erratum: Multiple cycles of dose-intensive chemotherapy with repeated stem cell support as induction treatment in metastatic breast cancer: a feasibility study [PDF]
Susana García-Rayo+9 more
openalex +1 more source
Anti-programmed death-1 inhibitors and nimotuzumab in combination with induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma: a propensity score-matched analysis. [PDF]
Zhang YN+6 more
europepmc +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Long-term results of locoregionally advanced nasopharyngeal carcinoma treated with cisplatin and 5-fluorouracil induction chemotherapy with or without docetaxel in young and middle aged adults. [PDF]
Zheng Y, Xue F, Ou D, Niu X, Hu C, He X.
europepmc +1 more source
A dual‐functional hafnium oxide nanoplatform is developed for enhanced cancer radiotherapy. This innovative system combines the inherent radiosensitizing properties of high‐Z hafnium oxide with Bcl‐2 gene‐silencing capabilities. The nanoplatform demonstrated synergistic enhancement of radiotherapy efficacy through increased generation of reactive ...
Seungyong Shin+12 more
wiley +1 more source
Is the gemcitabin-cisplatin combination the optimal induction chemotherapy for non-Asian patients with nasopharyngeal carcinoma (NPC)? Insights from a cohort in northeastern Morocco. [PDF]
Talbi O+10 more
europepmc +1 more source
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar+4 more
wiley +1 more source
Erratum: Efficacy and Safety of Combined PD-1 Inhibitor with Induction Chemotherapy Followed by IMRT Plus Nimotuzumab in Locally Advanced Nasopharyngeal Carcinoma: A Retrospective Analysis [Corrigendum]. [PDF]
europepmc +1 more source
Efficacy and Safety of Combined PD-1 Inhibitor With Induction Chemotherapy Followed by IMRT Plus Nimotuzumab in Locally Advanced Nasopharyngeal Carcinoma: A Retrospective Analysis. [PDF]
Chen K, Huang X, Chen J, Zhang S.
europepmc +1 more source