Results 251 to 260 of about 1,011,263 (307)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

High-Power Hybrid Nanogenerator With Multi-Degree-of-Freedom Mechanical Coupling for Harvesting Water Wave Energy. [PDF]

Adv Sci (Weinh)
Ding S, Zhai H, Gong H, Long X, Tian Y, Hong Z, Zheng L, Wang X, Chen X, Wang ZL.   +9 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Energy-Aware Finite-Horizon MPC Coordination of Adaptive VSG Inertia and BESS Control for Transient-Stability Enhancement in Renewable-Dominated Low-Inertia Hybrid Microgrids. [PDF]

Sensors (Basel)
Rodríguez Romero JD, Hernández-Mayoral E, Gamboa SA, Torres-García V, Madrigal-Martínez M, Trujillo-Caballero JC, Jaramillo OA.   +6 more
europepmc   +1 more source

A dual doubly-fed generator system supplied by a five-phase voltage inverter. [PDF]

Sci Rep
Blecharz K, Kondratenko D.
europepmc   +1 more source

Implantation of an extravascular implantable cardioverter-defibrillator in a patient with retrosternal adhesions from epicardial leads implanted via a subxiphoid approach. [PDF]

HeartRhythm Case Rep
Douglas M, Gadre A, Crawford T, Serfas JD, Noheria A, Sheldon SH.   +5 more
europepmc   +1 more source

Athletes with Implantable Cardioverter-Defibrillators: A Practical Framework for Device Selection, Programming, and Return-to-Sport Risk Mitigation. [PDF]

J Clin Med
Sharp Dimitri D, Prutkin JM.
europepmc   +1 more source

Perioperative Management of Pediatric Epilepsy Neuromodulation Devices. [PDF]

Children (Basel)
Cha YM, Smith A, Benzon HA, Wong BJ.
europepmc   +1 more source

Research on the dynamic characteristics of a wind turbine drivetrain based on different control strategies for the generator-side inverter. [PDF]

PLoS One
Zhang S, Jia S, Zhao Y, Wei J, Ma Y, Wu L.   +5 more
europepmc   +1 more source

Subcutaneous implantable cardioverter-defibrillator system malfunction during pelvic radiation therapy: Recognition and management of a rare complication. [PDF]

HeartRhythm Case Rep
Rayfield C, Beaser AD, Ozcan C.
europepmc   +1 more source