Results 51 to 60 of about 93,320 (293)

Evolution of grain boundary character distribution in near-surface regions of a cold-rolled nickel-based superalloy during induction heating process

Journal of Materials Research and Technology, 2021
The influence of induction heating on the grain boundary character distribution (GBCD) in near-surface regions of a cold-rolled Nickel-based superalloy was researched.
Zhen Lu, Chengcai Zhang, Nana Deng, Haiping Zhou, Gang Wang, Yukuo Su, Ruirui Fang, Hongbin Zhang   +7 more
doaj  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Technology of flame‑induction heating of ferrous metal shavings in hot briquetting installations

Литьë и металлургия
As a result of the study of flame‑induction heating of steel and cast iron shavings, optimal heating modes, dimensions of the furnace and the ratio of the sizes of its components (gas‑flame and induction heaters) were established, which served as the ...
O. M. Dyakonov, V. Ju. Sereda
doaj   +1 more source

INDUCTION HEATING IN HISTORY AND DEVELOPMENT. APPLICATION IN MODERN TRANSPORT REPAIRING TECHNOLOGIES [PDF]

Avtomobilʹnyj Transport (Harʹkov), 2017
The technologies used in repair of vehicles were analyzed in the given paper. The shortcomings of the mechanical repair methods in question can be solved by using induction heating.
Yu. Batyhin, O. Sabokar, V. Strelnikova
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Transient heating of moving objects

Electrical engineering & Electromechanics, 2014
A mathematical model of transient and quasistatic heating of moving objects by various heat sources is considered. The mathematical formulation of the problem is described, examples of thermal calculation given.
E.I. Baida
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Numerical Simulation of the Moving Induction Heating Process with Magnetic Flux Concentrator

Advances in Mechanical Engineering, 2013
The induction heating with ferromagnetic metal powder bonded magnetic flux concentrator (MPB-MFC) demonstrates more advantages in surface heating treatments of metal. However, the moving heating application is mostly applied in the industrial production.
Feng Li, Xuekun Li, Tianxing Zhu, Yiming (Kevin) Rong   +3 more
doaj   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source