Results 51 to 60 of about 101,144 (266)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
AIP AdvancesThis study demonstrates rapid carbon nanotube (CNT) synthesis using a 150 kHz induction heating system, enabling precise temperature and pressure control in thermal chemical vapor deposition processes.
Jinho Choi +8 more
doaj +1 more source
Technology of flame‑induction heating of ferrous metal shavings in hot briquetting installations
Литьë и металлургияAs a result of the study of flame‑induction heating of steel and cast iron shavings, optimal heating modes, dimensions of the furnace and the ratio of the sizes of its components (gas‑flame and induction heaters) were established, which served as the ...
O. M. Dyakonov, V. Ju. Sereda
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 2011 The increasing demand for industrial furnace heaters has attracted a lot of attentions from researchers and practitioners. Traditional longitudinal method is inadequate to meet the ever increasing demand on quality performance in regard to temperature uniformity on the work strips, especially on thin and long strips.
Youhua Wang +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
INDUCTION HEATING IN HISTORY AND DEVELOPMENT. APPLICATION IN MODERN TRANSPORT REPAIRING TECHNOLOGIES [PDF]
Avtomobilʹnyj Transport (Harʹkov), 2017 The technologies used in repair of vehicles were analyzed in the given paper. The shortcomings of the mechanical repair methods in question can be solved by using induction heating.
Yu. Batyhin, O. Sabokar, V. Strelnikova
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source