Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
A Combined Model and Data-Driven Approach for the Determination of Rotor Temperature in an Induction Machine. [PDF]
Sensors (Basel), 2021 Mocanu R, Onea A, Dosoftei CC.
europepmc +1 more source
Data Engineering for the Analysis of Semiconductor Manufacturing Data [PDF]
, 1995 We have analyzed manufacturing data from several different semiconductor manufacturing plants, using decision tree induction software called Q-YIELD. The software generates rules for predicting when a given product should be rejected.
Turney, Peter
core +2 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
A Simple Linearization Method of Nonlinear Systems Based on Fuzzy Logic
IEEE AccessLinearization is a powerful tool that enables the analysis and control of nonlinear systems by simplifying their dynamics and allowing the use of well-established linear control techniques.
Daniela Perdukova +3 more
doaj +1 more source
Guaranteed State Estimation Using a Bundle of Interval Observers with Adaptive Gains Applied to the Induction Machine. [PDF]
Sensors (Basel), 2021 Schwartz M, Krebs S, Hohmann S.
europepmc +1 more source
Machine learning and grammar induction [PDF]
Machine Learning, 1987 Despite its complexity, the task of natural language processing can be divided into a number of well-defined subtasks, and one of these centers on syntax. This aspect of language has been studied in detail by linguists, and developmental studies have provided a variety of empirical generalizations about the stages that children traverse in their ...
openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Low-Computational-Cost Hybrid FEM-Analytical Induction Machine Model for the Diagnosis of Rotor Eccentricity, Based on Sparse Identification Techniques and Trigonometric Interpolation. [PDF]
Sensors (Basel), 2021 Terron-Santiago C +3 more
europepmc +1 more source
Design of Prototype Dynamic Ac Power Machine with Equivalent Circuit Modeling (Torque Speed Curve of Induction Motor 1,1, Kw) [PDF]
, 2017 Squirrel cage induction motors are widely used in electric motor drives due to their satisfactory mechanical characteristics (torque, current, overloading) and small dimensions, as well as their low price.
Abidin, Z. (Zainal), Adam, A. (Adam)
core