Results 81 to 90 of about 2,522,226 (288)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
An open source rule induction tool for transfer-based SMT [PDF]
, 2009 In this paper we describe an open source tool for automatic induction of transfer rules. Transfer rule induction is carried out on pairs of dependency structures and their node alignment to produce all rules consistent with the node alignment.
Graham, Yvette, van Genabith, Josef
core +2 more sources
Genetic Algorithm Approach for Gains Selection of Induction Machine Extended Speed Observer
Energies, 2020 The subject of this paper is gains selection of an extended induction machine speed observer. A high number of gains makes manual gains selection difficult and due to nonlinear equations of the observer, well-known methods of gains selection for linear ...
Daniel Wachowiak
doaj +1 more source
Inductive Confidence Machines for Regression [PDF]
, 2002 The existing methods of predicting with confidence give good accuracy and confidence values, but quite often are computationally inefficient. Some partial solutions have been suggested in the past. Both the original method and these solutions were based on transductive inference.
Harris Papadopoulos +3 more
openaire +2 more sources
Partial Inductance Model of Induction Machines for Fault Diagnosis [PDF]
Sensors, 2018 The development of advanced fault diagnostic systems for induction machines through the stator current requires accurate and fast models that can simulate the machine under faulty conditions, both in steady-state and in transient regime. These models are far more complex than the models used for healthy machines, because one of the effect of the faults
Manuel Pineda-Sánchez +5 more
openaire +5 more sources
Computationally efficient induction of classification rules with the PMCRI and J-PMCRI frameworks [PDF]
, 2012 In order to gain knowledge from large databases, scalable data mining technologies are needed. Data are captured on a large scale and thus databases are increasing at a fast pace.
Stahl, Frederic, Bramer, Max, Bramer, M.
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
IEEE AccessIn traditional motor current signature analysis (MCSA) approach, the spectral leakage of the fundamental supply frequency can obscure the characteristic fault component under low-load or no-load conditions.
Reza Bazghandi +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source