Results 71 to 80 of about 2,522,226 (288)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An application of decision trees method for fault diagnosis of induction motors [PDF]

, 2006
Decision tree is one of the most effective and widely used methods for building classification model. Researchers from various disciplines such as statistics, machine learning, pattern recognition, and data mining have considered the decision tree ...
Yang, Bo-Suk, Tran, Van Tung, Oh, Myung-Suck   +2 more
core   +3 more sources

Advanced Residual Optimal Mapping Approach for Precise Detection of Stator Faults in Induction Motors

IEEE Access
Induction motors, known for their reliability and efficiency, are widely used in various industrial applications. However, their susceptibility to failure, particularly in harsh environments, poses significant operational challenges.
Abderrahim Allal, Zakaria Lammouchi, Abderrahmane Khechekhouche, Naoui Mohamed, Khalid Alqunun, Amer Alghadhban, Ismail Marouani, Tawfik Guesmi   +7 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Experimental analysis for star and open-end stator winding structures of IM

Power Electronics and Drives
This article focuses on the scalar control of four induction machine structures: the conventional induction machine, the double-star machine, the open-ended stator winding machine and the dual open-end stator winding machine.
Nayli Abdelmonoem, Guizani Sami, Ben Ammar Faouzi   +2 more
doaj   +1 more source

Innovative Application of Statistical Sound Analysis for Fault Diagnosis in Variable-Speed Induction Machines [PDF]

EPJ Web of Conferences
The article presents an innovative method leveraging statistical sound analysis to diagnose malfunctions in variable-speed drive-controlled (VSD) induction machines (IM).
El Idrissi Abderrahman, Derouich Aziz, Mahfoud Said, El Ouanjli Najib, Chojaa Hamid, Chantoufi Ahmed   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source