Results 121 to 130 of about 2,797,644 (402)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Design of Motor Current Signature Analyses (MCSA) Based on LabVIEW for Online Detection of Induction Motor Faults

open access: yesJAREE (Journal on Advanced Research in Electrical Engineering), 2017
Induction motor is the most common used electric motor in industry. Along with its operation, induction motor can savere certain damage which is generally dominated by internal fault, such as s rotor fault, stator fault, and bearing fault. In this paper,
Dimas Anton Asfani   +6 more
doaj  

Implementasi Sub Unit Kompetensi Merencanakan, Mempersiapkan Pekerjaan Dan Membongkar Motor Induksi Pada Mata Kuliah Praktikum Pemeliharaan Mesin Listrik [PDF]

open access: yes, 2013
Induction Motor Electric Motor is the type most widely used in the industries both large, medium and small scale industries. For prime movers, for the operation of Induction Motors often serve varying load, so that frequent Induction Motor disorder ...
Hidayat, E. P. (Edy)   +2 more
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

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