Results 141 to 150 of about 190,705 (314)

Induction Motor Speed Control Based on Inverse System Theory and Sliding Mode Method

open access: yesGong-kuang zidonghua, 2012
For the problem that parameter uncertainty was usually neglected when inverse system theory was used in speed regulation system of induction motor, on the basis of non-linear model of induction motor, a pseudo-linear control system model of induction ...
NIU Chao, ZHU Zhen-wei, CAO Ling-zhi
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Quasi-3D Evaluation Method for Optimizing Low-Speed High-Torque Induction Motors with Matrix-Rotor Structure

open access: yes
Permanent magnet machines have been the pinnacle of performance in low-speed high-torque applications, although several unsuccessful attempts have been made to propose suitable induction machine solutions for direct-drive scenarios.
Jara, Werner   +4 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Thermal management analyses of induction motor through the combination of air-cooling and an integrated water-cooling system. [PDF]

open access: yesSci Rep, 2023
Madhavan S   +7 more
europepmc   +1 more source

Induction Motor Parameter Identification from Operational Data

open access: yes, 2007
Among the parameters of an induction motor, the dynamics are largely characterised by Inertia (H) and torque-damping factor (B). It is now simple to get substation bus bar data (current and voltage) by using phasor measurement device.
Palmer, Edward W.   +2 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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