Results 141 to 150 of about 2,741,614 (378)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Sensor Fault Diagnosis Method Based on Rotor Slip Applied to Induction Motor Drive. [PDF]

Sensors (Basel), 2022
Tran CD, Kuchar M, Sobek M, Sotola V, Dinh BH.   +4 more
europepmc   +1 more source

Motor power control circuit for ac induction motors [PDF]

, 1983
A motor power control of the type which functions by controlling the power factor wherein one of the parameters of power factor current on time is determined by the on time of a triac through which current is supplied to the motor. By means of a positive
Nola, F. J.
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Modeling of high voltage induction motor cooling system using linear regression mathematical models. [PDF]

PLoS One, 2022
Rosli NS, Ibrahim R, Ismail I, Omar M.
europepmc   +1 more source

Simple Classroom Demonstration of Lenz's Law and the ac Induction Motor [PDF]

, 1965
P. W. Matthews
openalex   +1 more source

The induction motor [PDF]

, 1904
Citation: Matthews, Howard David and Dial, Thomas E. The induction motor. Senior thesis, Kansas State Agricultural College, 1904.Morse Department of Special CollectionsIntroduction:The induction motor is a type of alternating current motor in which the ...
Dial, Thomas E., Matthews, Howard David
core  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Fuzzy Reasoning Numerical Spiking Neural P Systems for Induction Motor Fault Diagnosis. [PDF]

Entropy (Basel), 2022
Yin X, Liu X, Sun M, Dong J, Zhang G.
europepmc   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source