Results 41 to 50 of about 173,489,929 (299)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

The Labor-Induced Pregnancy Cases In Dr Soetomo General Hospital: A Descriptive Study

Medical and Health Science Journal, 2021
Background: Labor induction is a procedure to stimulate uterine contractions during pregnancy before labor begins on its own to achieve a vaginal birth with medical or mechanical intervention to start the labor.
Alfin Firasy
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

The assessment of labor induction efficacy in inpatient department [PDF]

РМЖ. Мать и дитя, 2020
D.L. Guryev1,2, M.B. Okhapkin2, D.D. Guryeva2, I.V. Kabanov2, M.S. Gureva1, L.N. Nidershtrat1, T.A. Sorokina1 1Regional Perinatal Center, Yaroslavl, Russian Federation 2Yaroslavl State Medical University ...
D.L. Guryev, M.B. Okhapkin, D.D. Guryeva, I.V. Kabanov, M.S. Gureva, L.N. Nidershtrat, T.A. Sorokina   +6 more
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Outpatient labor induction—Exploring future potential by assessing eligibility in a historical cohort

Acta Obstetricia et Gynecologica Scandinavica
Introduction Labor induction rates have increased over the last decades, and in many high‐income countries, more than one in four labors are induced. Outpatient management of labor induction has been suggested in low‐risk pregnancies to improve women's ...
Kjersti Engen Marsdal, Ingvil Krarup Sørbye, Stine Bernitz, Ranveig Elise T. Sve, Kristine Ask, Mirjam Lukasse   +5 more
doaj   +1 more source

Leisure and Hospitality Employment: Kansas Statewide; 3rd Quarter 2019 / presented by the Kansas Department of Labor.

, 2020
March 16, 2020. Information provided to the Kansas Legislature, House Committee on Commerce, Labor and Economic Development, presented by the Kansas Department of Labor. Presentation date and committee name taken from Kansas Legislature website. "Source:
Kansas. Department of Labor.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Clinical outcomes and feasibility of implementing outpatient labor induction with misoprostol: A prospective cohort study

Acta Obstetricia et Gynecologica Scandinavica
Introduction In response to the increasing rates of induction of labor (IOL), outpatient IOL has emerged as a potential approach to enhance women's satisfaction while reducing costs and staffing requirements.
Kjersti Engen Marsdal, Ingvil Krarup Sørbye, Stine Bernitz, Nasreen Adan, Elin Baustad Grødal, Anne Flem Jacobsen, Mirjam Lukasse   +6 more
doaj   +1 more source