Results 71 to 80 of about 26,033 (291)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Nuchal cord entanglement and outcome of labour induction [PDF]

, 2007
AIM OF THE STUDY: To assess whether nuchal cord entanglement would affect the outcome of elective labour induction. METHOD: In a group of pregnant women, the outcome of elective labour induction was evaluated in relation to a list of possibly ...
Ghi T, Morandi R, Pilu G, D'Emidio L, Casadio P, Pelusi G   +5 more
core   +1 more source

Reducing caesarean delivery: An economic evaluation of routine induction of labour at 39 weeks in low‐risk nulliparous women

, 2019
Background: Clinical interventions known to reduce the risk of caesarean delivery include routine induction of labour at 39 weeks, caseload midwifery and chart audit, but they have not been compared for cost-effectiveness.
Anne Sneddon, Debra K. Creedy, Haylee Fox, Toohill, Jocelyn, Creedy, Debra K, Gamble, Jenny, Ellwood, David, Emily J. Callander, David Ellwood, Fox, Haylee, Jocelyn Toohill, Jenny Gamble, Sneddon, Anne, Callander, Emily J   +13 more
core   +1 more source

Mifepristone for induction of labour

Cochrane Database of Systematic Reviews, 2009
The steroid hormone, progesterone, inhibits contractions of the pregnant uterus at all gestations. Antiprogestins (including mifepristone) have been developed to antagonise the action of progesterone, and have a recognised role in medical termination of early or mid-trimester pregnancy.
Dharani, Hapangama, James P, Neilson
openaire   +3 more sources

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Failed induction of labor and associated factors among women receiving induction at public hospitals of Kembata zone in central Ethiopia

BMC Pregnancy and Childbirth
Background Failed induction of labour contributes to high caesarean section rates, posing risks to both maternal and neonatal health. Despite its clinical importance, limited data exists on the prevalence and determinants of failed induction of labour in
Arega Abebe Lonsako, Teshale Tilahun, Mulatu Wolde, Tariku Laelago, Tsehaynew Kasse, Asfaw Anulo, Addisu Girma   +6 more
doaj   +1 more source

Perinatal mortality associated with induction of labour versus expectant management in nulliparous women aged 35 years or over: An English national cohort study.

PLoS Medicine, 2017
BackgroundA recent randomised controlled trial (RCT) demonstrated that induction of labour at 39 weeks of gestational age has no short-term adverse effect on the mother or infant among nulliparous women aged ≥35 years. However, the trial was underpowered
Hannah E Knight, David A Cromwell, Ipek Gurol-Urganci, Katie Harron, Jan H van der Meulen, Gordon C S Smith   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Women and birth partners’ experiences of cervical ripening at home and in hospital

BMC Pregnancy and Childbirth
Background In the United Kingdom, induction of labour rates are rapidly rising, and around a third of pregnant women undergo the procedure. The first stage, cervical ripening, traditionally carried out in hospital, is increasingly offered outpatient – or
Cassandra Yuill, Mairi Harkness, Helen Cheyne, Boo Charkin, Monica Ferreira, Eloise Price, Amarnath Bhide, Mairead Black, Kathleen Boyd, Neelam Heera-Shergill, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Sarah J. Stock, Rosemary Townsend, Linda J. Williams, Christine McCourt   +17 more
doaj   +1 more source

Induction of labour with sequential double-balloon catheter and oral misoprostol versus oral misoprostol alone in obese women

European Journal of Obstetrics & Gynecology and Reproductive Biology: X, 2019
Objective: To evaluate the efficacy of induction of labour in obese women using sequential double-balloon catheter and oral misoprostol in comparison with oral misoprostol alone. Study design: In this cohort study, 400 pregnant women with BMI higher than
Sven Kehl, Tilman Born, Christel Weiss, Florian Faschingbauer, Jutta Pretscher, Matthias W. Beckmann, Marc Sütterlin, Ulf Dammer   +7 more
doaj   +1 more source