Carboprost versus Oxytocin as the first-line treatment of primary postpartum haemorrhage (COPE): protocol for a phase IV, double-blind, double-dummy, randomised controlled trial and economic analysis [PDF]
Introduction Excessive bleeding after childbirth (postpartum haemorrhage, PPH) affects 5% of births and causes 75 000 maternal deaths worldwide annually.
Kerry Woolfall +26 more
doaj +2 more sources
Postabortion care availability, readiness, and accessibility in Niger in 2022: results from linked facility-female cross-sectional data [PDF]
Background Postabortion care (PAC), which is an essential element of emergency obstetric care, is underresearched in Niger. The study aims to assess the availability, readiness, and accessibility of facility-based PAC services in Niger.
Haley L. Thomas +4 more
doaj +2 more sources
When Is Postpartum Haemorrhage Treatment Initiated? A Nested Observational Study Within the E-MOTIVE Trial. [PDF]
ABSTRACT Objective To compare the frequency and timing of postpartum haemorrhage (PPH) treatment initiation between hospitals implementing the MOTIVE treatment bundle (which consisted of uterine Massage, Oxytocic drugs, Tranexamic acid, IntraVenous fluids and Examination) and those following usual care.
Mammoliti KM +32 more
europepmc +2 more sources
Igniting the spark in six countries to transform the trajectory of postpartum hemorrhage across the globe: An overview of the AMPLI-PPHI project. [PDF]
Abstract Postpartum hemorrhage (PPH) remains the leading cause of maternal mortality worldwide, disproportionately affecting women in low‐ and middle‐income countries. Despite updated WHO recommendations and the availability of newer technologies—including heat‐stable carbetocin, tranexamic acid as part of a clinical care bundle, misoprostol, and ...
Roman E.
europepmc +2 more sources
Background: Reducing maternal and neonatal mortality and morbidity are major public health concern globally and demands policies and commitments, strategy formulations and implementation and improved health-care service delivery and management.
Ishmael D Jaja, Michael Promise Ogolodom
doaj +1 more source
Efficacy of B-Lynch compression suture for control of intractable hemorrhage during cesarean section
Background: Primary postpartum hemorrhage (PPH) due to atonicity during lower segment cesarean section is commonly seen in obstetric practice. Usually, it responds to uterotonics but at times it may lead to life-threatening complications.
Priya Manohar Bagade
doaj +1 more source
To study the efficacy of misoprostol compared with methyl ergometrine for prevention of postpartum haemorrhage [PDF]
Objective: Present study was conducted to study the safety and efficacy of misoprostol and methyl ergometrine when used in the prevention of postpartum haemorrhage (PPH).
Varsha Kotwal
doaj +1 more source
Comparative study of Foley’s catheter and prostaglandin E2 gel for pre-induction cervical ripening
Background: Induction of labor is a crucial and customary clinical procedure in obstetrics. It is arguably one of the most abused procedures. Cervical ripening determines the success of delivery.
Shruti J Shetty +3 more
doaj +1 more source
Quality, availability and storage conditions of oxytocin and misoprostol in Malawi
Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality in low- and middle-income countries (LMICs). Oxytocin and misoprostol are used for the prevention and treatment of PPH. However, both medicines are chemically unstable and
Nhomsai Hagen, Felix Khuluza, Lutz Heide
doaj +1 more source
Effect of Intravenous Tranexamic Acid Administration on Blood Loss during and after Caesarean Delivery: A Randomised Controlled Study [PDF]
Introduction: India remains a major contributor to maternal deaths in the world. Haemorrhage after delivery (both vaginal & caesarean) is the leading cause. To reduce the haemorrhage, oxytocics are routinely used. In heavy bleeding, blood transfusion
Shyamali Dutta +2 more
doaj +1 more source

