Results 31 to 40 of about 26,275 (301)

Clinical Audit of Ovulation Induction at Qena university and Qus Hospitals

SVU - International Journal of Medical Sciences
Background: In one in six couples, infertility may be caused by male, female, or mixed causes, with some instances unexplained. Ovulatory abnormalities cause 30% of infertility.
Mahmoud Souliman Iwes , Nema AboAlhagag Mohamad , Mahmoud Ibrahim Almolakab Bel Alrashedy , Mohammed Abdelrahman Mohammed   +3 more
doaj   +1 more source

Spontaneous ovarian hyperstimulation syndrome with primary hypothyroidism: Imaging a rare entity

Radiology Case Reports, 2015
Ovarian hyperstimulation syndrome is a disorder associated with ovulation induction and is rarely seen in pregnant women. Very few cases of spontaneous ovarian hyperstimulation syndrome have been reported in a woman who is neither pregnant nor undergoing
Subramanian Ilanchezhian, MBBS, MD, Shubha Veppur Mohan, MBBS, Rajoo Ramachandran, MBBS, MD, Sellappan Rajamanickam Babu, MBBS, MD   +3 more
doaj   +1 more source

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

A romatase enzyme inhibitor versus gonadotropin for induction of ovulation in patients with polycystic ovary syndrome resistant to clomiphene citrate a randomized controlled trial [PDF]

Minia Journal of Medical Research, 2019
Introduction: Clomiphene citrate (CC) is the first drug used to induce ovulation in patients with poly cystic ovary syndrome (PCOS). Although 70–80% of such women ovulate when treated with CC, only 40% become pregnant (van Wely et al., 2005).
Osama Abd El Aziz, Alaa Abd El-Azeem, Haitham Bahaa El-Din, Hossam Eldin Abd-Allah   +3 more
doaj   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Association of anti-mullerian hormone and free androgen index level on response to clomiphene citrate in PCOS infertile women

Gynecology and Obstetrics Clinical Medicine, 2022
Background: Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility. Clomiphene citrate, insulin-sensitizing drugs, aromatase inhibitors, gonadotropins, or laparoscopic ovarian drilling are various methods used for ovulation ...
Jasmine Kavitha Washington, Jayasree Manivasakan, Poomalar Gunasekaran Kala, Sasikala R.   +3 more
doaj   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Revisiting ovulation induction in PCOS

, 2014
Polycystic ovary syndrome (PCOS) is associated with anovulatory infertility. Many clinicians focus on the use of assisted reproductive technologies other than medical induction of ovulation.
Bart C. J. M. Fauser, Fauser, B.C.J.M.
core   +1 more source

From Cytoskeletal Remodeling to Oocyte Quality: The Emerging Role of Mechanics

Advanced Science, EarlyView.
Mechanical properties of the oocyte are increasingly recognized as critical determinants of meiotic success and developmental potential. How actomyosin remodeling controls oocyte mechanics, how these properties are altered in pathological conditions, and how they could serve as markers in reproductive medicine are examined.
Anastasia Shihabi, Rose Bulteau, Lucie Barbier, Marie‐Emilie Terret   +3 more
wiley   +1 more source