Results 51 to 60 of about 13,274 (262)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Three-level boost converter with zero voltage transition

The Journal of Engineering, 2017
As compared with the traditional boost converter, the three-level boost converter possesses several advantages, such as lower switch voltage stresses and lower inductor current ripple.
Kuo-Ing Hwu, Jenn-Jong Shieh, Wen-Zhuang Jiang   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Calculation of fields and currents in the induction system with the attractive screen and the additional coil as a tool for the straightening

Electrical engineering & Electromechanics, 2015
In the idealization of the "limiting low" frequencies of acting fields the calculated dependences for the density of the induced currents and distributed force of the attractive in the induction system with attractive screen and the external additional ...
Yu.V. Batygin, E.A. Chaplygin, S.A. Shinderuk   +2 more
doaj  

Analysis of IEC 60310:2016 Railway Application—Traction Transformer and Inductor on Board Rolling Stock

机车电传动, 2020
In order to facilitate the relevant personnel in the rail transit industry correctly understand and implement IEC 60310:2016 Railway application—Traction transformer and inductor on board rolling stock, the standard was explained from the aspect of ...
Delong YANG
doaj  

Determination of the law of probability density distribution of colony-forming units number under livestock waste disinfection

Advanced Engineering Research, 2017
Introduction. An advanced technique of the livestock waste disinfection is considered. The essence of the method is in the integral physicochemical action of the alternating magnetic field combined with a chemical agent.
Nikolay V. Limarenko, Victor P. Zharov
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Additive Manufacturing as an Insulator for Medium Voltage Power Electronics Applications

IEEE Access
The use of additive manufacturing (AM), more especially 3D printing, to medium voltage power electronics is examined in this research. It focuses on how this technology may transform insulating techniques and component manufacture.
Faisal Alsaif
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source