Results 41 to 50 of about 708 (267)

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Design and Optimization Approach for the Magnetic Components of a Five-Level Current Source Rectifier

Eletrônica de Potência, 2021
This work presents a design and optimization method of the five-level current source converter magnetics components, this is a contribution of this work, since the magnetics volume information of this topology lacks in the literature.
Lisandra K. Reis, Marcelo L. Heldwein
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Magnetic properties of an ACSR conductor steel core at temperatures up to 230 ∘C and their impact on the transformer effect

IET Science, Measurement & Technology, 2021
The current density distribution between layers of steel‐reinforced conductors having an odd number of aluminum layers is modified by the transformer effect, as a result of the steel core magnetisation.
Ruyguara A. Meyberg, Farith M. Absi Salas, Luis Adriano M. C. Domingues, Márcio A. Sens, Maria Teresa Correia de Barros, Antonio C. S. Lima   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evaluation of Filtered Spark Gap on the Lightning Protection of Distribution Transformers: Experimental and Simulation Study

Energies, 2020
Protection of transformers, as one of the most expensive equipment in the power system, against lightning overvoltage impulses is a vital task. This paper, for the first time so far, investigates the effects of a filtered spark gap on the protection ...
Mahdi Pourakbari-Kasmaei, Farhan Mahmood, Michal Krbal, Ludek Pelikan, Jaroslava Orságová, Petr Toman, Matti Lehtonen   +6 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Review of coupled inductors in power electronics: From concept to practice

e-Prime: Advances in Electrical Engineering, Electronics and Energy
With the increasing complexity of power electronics converters, magnetic components like inductors, transformers in different configurations, etc., play important roles in shaping a power controller to meet its desired performance effectively and ...
A.K. Paul, Sai Ram B․, S.V. Kulkarni
doaj   +1 more source

First self‐resonant frequency of power inductors based on approximated corrected stray capacitances

IET Power Electronics, 2021
Inductive devices are extensively employed in power electronic systems due to their magnetic energy storage and power transfer capabilities. The current trend is towards increasing the frequency of operation in order to reduce the size of the magnetic ...
Ignacio Lope, Claudio Carretero, Jesus Acero   +2 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source