Results 51 to 60 of about 708 (267)

Next-Generation Active-Clamp Forward-Flyback Converter With Integrated Planar Transformer for 4 kW LDC

open access: yesIEEE Access
This paper proposes a single-module Active-Clamp Forward-Flyback (ACFF) converter for the next-generation low-voltage DC-DC converter (LDC) ensuring 4kW output power.
Gyeong-Hyun Kwon   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analytical Models for HF-Losses of Litz Wire in Inductors With Arbitrary Winding and Gap Arrangements

open access: yesIEEE Open Journal of Power Electronics
Dueto 2D fields in the core window of inductors (e.g. the fringing field caused by core gaps) large errors can occur in the winding loss calculation, when the assumptions, that the $H$-field is parallel to the winding layers and constant along the field ...
Qingchao Meng, Jurgen Biela
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Spray-coated magnetic powder composite planar inductor for compact IoT sensor node

open access: yesAIP Advances, 2020
A spray coating process of magnetic powder composite material is proposed in this paper for planar inductors and transformers for small DC/DC converter.
T. Hara, M. Yamaguchi
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Fault Tolerant Dual Active Bridge Converter for Electric Vehicle Application [PDF]

open access: yesIranian Journal of Electrical and Electronic Engineering
In this paper, a dual-active bridge converter based on the utilization of two transformers is presented. The principles of operation, switching strategy, and transmission power characteristics of the proposed converter under normal operation are ...
Milad Babalou   +3 more
doaj  

3D structure design of magnetic ferrite cores using gelcasting and pressure-less sintering process

open access: yesAIP Advances, 2019
Gelcasting is a well established process for ceramics manufacturing which recently has been proved to be successful for soft ferrites as well. This approach is particularly interesting for power electronics application in which the magnetic components (e.
A. Stratta   +6 more
doaj   +1 more source

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