Results 51 to 60 of about 631 (218)

Next-Generation Active-Clamp Forward-Flyback Converter With Integrated Planar Transformer for 4 kW LDC

IEEE Access
This paper proposes a single-module Active-Clamp Forward-Flyback (ACFF) converter for the next-generation low-voltage DC-DC converter (LDC) ensuring 4kW output power.
Gyeong-Hyun Kwon, Dong-In Lee, Seong-Wook Jeong, Han-Shin Youn   +3 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Analytical Models for HF-Losses of Litz Wire in Inductors With Arbitrary Winding and Gap Arrangements

IEEE Open Journal of Power Electronics
Dueto 2D fields in the core window of inductors (e.g. the fringing field caused by core gaps) large errors can occur in the winding loss calculation, when the assumptions, that the $H$-field is parallel to the winding layers and constant along the field ...
Qingchao Meng, Jurgen Biela
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Spray-coated magnetic powder composite planar inductor for compact IoT sensor node

AIP Advances, 2020
A spray coating process of magnetic powder composite material is proposed in this paper for planar inductors and transformers for small DC/DC converter.
T. Hara, M. Yamaguchi
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Fault Tolerant Dual Active Bridge Converter for Electric Vehicle Application [PDF]

Iranian Journal of Electrical and Electronic Engineering
In this paper, a dual-active bridge converter based on the utilization of two transformers is presented. The principles of operation, switching strategy, and transmission power characteristics of the proposed converter under normal operation are ...
Milad Babalou, Hossein Torkaman, Edris Pouresmaeil, Nazanin Pourmoradi   +3 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

3D structure design of magnetic ferrite cores using gelcasting and pressure-less sintering process

AIP Advances, 2019
Gelcasting is a well established process for ceramics manufacturing which recently has been proved to be successful for soft ferrites as well. This approach is particularly interesting for power electronics application in which the magnetic components (e.
A. Stratta, B. Ahmadi, B. Mouawad, S. Robertson, L. De Lillo, L. Empringham, M. Johnson   +6 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source