Results 31 to 40 of about 2,341,621 (287)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Identification and analysis of research trends in industrial engineering in the papers published between January 2012 to January 2015

open access: yesآموزش مهندسی ایران, 2015
In the recent decades, amount of researches in the field of industrial engineering grew increasingly which makes hard to find a new area in this field. Indeed it needs extensive searches on the many published papers related to the field.
Abdullah Aghaei, Mojtaba Hajian Heydari
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Evaluation of the Palestinian Industrial Needs for Fields and Curricula of Academic Engineering Programs

open access: yesالمجلة العربية لضمان جودة التعليم الجامعي, 2011
This study evaluates the level of coordination between academic and industrial sectors in Palestine. It explores the development prospective for future studies.
Maher Al-Jabari
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

The role of gender on academic performance in STEM-related disciplines: Data from a tertiary institution

open access: yesData in Brief, 2018
This data article presents data of academic performances of undergraduate students in Science, Technology, Engineering and Mathematics (STEM) disciplines in Covenant University, Nigeria.
Temitope M. John   +7 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

THE INFLUENCE OF LEARNING OUTCOMES PRODUCTIVE SUBJECTS AND SELF-RELIANCE LEARNING WITH ACHIEVEMENT INDUSTRIAL WORK PRACTICES STUDENTS OF GRADE XII ELECTRONICS ENGINEERING SKILLS PROGRAM AT SMKN 3 YOGYAKARTA ACADEMIC YEAR 2012/2013 [PDF]

open access: yes, 2013
This study aimed to determine: (1) the influence of Learning Outcomes Productive Subjects with Achievement Industrial Work Practices students of grade XII Electronics Engineering Skills Program at SMKN 3 Yogyakarta Academic Year 2012/2013.
Afni Nur, Anita
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Integrating Challenge-Based-Learning, Project-Based-Learning, and Computer-Aided Technologies into Industrial Engineering Teaching: Towards a Sustainable Development Framework

open access: yesИнтеграция образования, 2022
Introduction. Teaching industrial engineering in the second decade of the 21st century requires problem-solving and decision-making competencies oriented towards sustainable development.
Roberto Pérez-Rodríguez   +6 more
doaj   +1 more source

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