Results 21 to 30 of about 3,414,860 (299)
Development of a Stress Sensor for Solids
Железобетонные конструкцииThe paper presents the results of experimental design of a cortex of the embedded stress sensor, which allows to determine stresses in the cross-section of large-scale laboratory monolithic structures made on the basis of mineral and polymer binders ...
N. N. Trekin +4 more
doaj +1 more source
Buildings 2019 Best Paper Awards
, 2021 Buildings is instituting the Best Paper Award to recognize outstanding papers published in the journal [...
Buildings Editorial Office Buildings Editorial Office
core +1 more source
High resilience prefabricated systems for the industrial buildings in seismic areas
Techne, 2018 This article deals with the topic of seismic vulnerability of single-storey industrial buildings, proposing the design of a new system able to support the movement of the load-bearing structure during earthquakes.
Eleonora Chesi +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Nature Communications, 2018 Pathway optimization and chassis engineering are usually carried out in a step-wise and trial-and-error manner. Here the authors present ’SCRaMbLE-in’ that combines in-vitro pathway rapid prototyping with in-vivo genome integration and optimization.
Wei Liu +12 more
doaj +1 more source
Buildings, 2021 The latest earthquakes in Europe exposed some critical problems in the connections of cladding panels in industrial precast reinforced concrete (PRC) structures.
Liana Ostetto +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Numerical Methods for Topological Optimization of Wooden Structural Elements
BuildingsTimber represents a building material that aligns with the environmental demands on the impact of the construction sector on climate change. The most common engineering solution for modern timber buildings with large spans is glued laminate timber ...
Daniela Țăpuși +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source