Results 51 to 60 of about 4,620,326 (308)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Numerical Methods for Topological Optimization of Wooden Structural Elements

Buildings
Timber represents a building material that aligns with the environmental demands on the impact of the construction sector on climate change. The most common engineering solution for modern timber buildings with large spans is glued laminate timber ...
Daniela Țăpuși, Andrei-Dan Sabău, Adrian-Alexandru Savu, Ruxandra-Irina Erbașu, Ioana Teodorescu   +4 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Performance Assessment of Wood-Based Composite Materials Subjected to High Temperatures

Buildings
This paper is based on research placed within the broader framework of the growing environmental impact requirements of building materials. Given this context, wood-based composite materials have emerged as a promising and innovative solution for ...
Ruxandra Irina Erbașu, Andrei-Dan Sabău, Daniela Țăpuși, Ioana Teodorescu   +3 more
doaj   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Techno-Economic Assessment of Net Metering and Energy Sharing in a Mixed-Use Renewable Energy Community in Montreal: A Simulation-Based Approach Using Tool4Cities

Energies
The study presents a scalable decision-support framework to assess energy-sharing strategies within mixed-use urban districts, with a focus on planning, sustainability, and policy relevance. Two renewable energy-sharing mechanisms—energy sharing (ES) and
Athena Karami Fardian, Saeed Ranjbar, Luca Cimmino, Francesca Vecchi, Caroline Hachem-Vermette, Ursula Eicker, Francesco Calise   +6 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

Nature Communications, 2018
Pathway optimization and chassis engineering are usually carried out in a step-wise and trial-and-error manner. Here the authors present ’SCRaMbLE-in’ that combines in-vitro pathway rapid prototyping with in-vivo genome integration and optimization.
Wei Liu, Zhouqing Luo, Yun Wang, Nhan T. Pham, Laura Tuck, Irene Pérez-Pi, Longying Liu, Yue Shen, Chris French, Manfred Auer, Jon Marles-Wright, Junbiao Dai, Yizhi Cai   +12 more
doaj   +1 more source

Profitability of Batteries in Photovoltaic Systems for Small Industrial Consumers in Spain under Current Regulatory Framework and Energy Prices

Energies, 2022
In recent years, important regulatory changes have been introduced in Spain in the fields of self-consumption and energy tariffs. In addition, electricity prices have risen sharply, reaching record highs in the last year.
Fernando Echevarría Camarero, Ana Ogando-Martínez, Pablo Durán Gómez, Pablo Carrasco Ortega   +3 more
doaj   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

Advanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar, David Osman Busse, Maximilian Sprengel, Domenico Furfari, Marc‐André Nielsen, Guilherme Abreu Faria, Jérémy Epp   +6 more
wiley   +1 more source