Results 31 to 40 of about 11,878,537 (285)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Scientific ReportsIn-vehicle information system (IVIS) use is prevalent among young adults. However, their interaction with IVIS needs to be better understood. Therefore, an on-road study aims to explore the effects of input modalities and secondary task types on young ...
Qi Zhong +4 more
doaj +1 more source
Influence of Age and Palm Surface Area on Secondary Task Performance in a Driving Simulator
Promet (Zagreb)Gesture control allows for reduced glance interaction compared to touchscreens when controlling secondary functions in cars. However, to date, there has been a lack of research investigating the influence of age and palm surface area (PSA) on performance
Lukas FUCHS +3 more
doaj +1 more source
Studying Industrial Design: exploring the experience of the female students [PDF]
, 2015 Despite a significant increase in the number of women enrolling and graduating from design courses, the reality is that women remain ‘invisible’ in the design profession (Bruce, 1985).
Miller, Evonne +3 more
core
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Design Heuristics in ideation across engineering and industrial design domains [PDF]
, 2010 How do designers explore a design space to generate diverse solutions? This work focuses on the identification of design heuristics used in the ideation process in the domains of industrial design and engineering design.
Gonzalez, Richard +3 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
, 2008 Presented on January 30, 2008, 6:00 PM – 7:00 PM, Klaus Advanced Computing Building, Seminar Room 1116Runtime: 58:15 minutesCarla Diana will talk about her experience as an industrial and interaction designer dealing with user experiences both digital ...
Diana, Carla
core +1 more source
The factors affecting the performance of the tunnel wall drilling task and their priority
Scientific ReportsClarifying the relationship between the man–machine environment and its impact on the tunnel wall drilling task performance (TWDTP) is crucial for enhancing the task performance.
Peng-Fei Gao +7 more
doaj +1 more source
Negotiating Learning Goals with Your Future Learning-Self
Technologies, 2022 This paper discusses the challenges towards designing an educational avatar which visualizes the future learning-self of a student in order to promote their self-regulated learning skills.
Konstantinos Tsiakas +5 more
doaj +1 more source