Results 31 to 40 of about 362,753 (265)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The factors affecting the performance of the tunnel wall drilling task and their priority

Scientific Reports
Clarifying the relationship between the man–machine environment and its impact on the tunnel wall drilling task performance (TWDTP) is crucial for enhancing the task performance.
Peng-Fei Gao, Jin-Yi Zhi, Ji-Dong Hu, Jin Wang, Yong-Sheng Xu, Rui Zou, Tie-Cheng Ding, Lin Yang   +7 more
doaj   +1 more source

Sustainability Design in Industry and Academia

2024 10th International Conference on ICT for Sustainability (ICT4S)
Sustainability design involves the design of sustainable software systems. There is a growing need to integrate sustainability issues into software development; therefore, many approaches have been developed in recent years. A widely used approach for sustainability design, the Sustainability Analysis Framework (SusAF), is applied in three cases, two ...
Chasanidou, Dimitra, Krogstie, John, Boletsis, Costas, Gasparini, Andrea Alessandro   +3 more
openaire   +2 more sources

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Automation Potential in the Workflow of a Scrub Nurse [PDF]

Interdisciplinary Description of Complex Systems
One of the heavily burdened actors in the operating theatre is the scrub nurse who is responsible for the organized and orderly workflow in the operating theatre.
Peter Schmid, Max B. Schäfer, Nina M. Stadel, Peter P. Pott, Thomas Maier   +4 more
doaj   +1 more source

Negotiating Learning Goals with Your Future Learning-Self

Technologies, 2022
This paper discusses the challenges towards designing an educational avatar which visualizes the future learning-self of a student in order to promote their self-regulated learning skills.
Konstantinos Tsiakas, Deborah Cnossen, Timothy H. C. Muyrers, Danique R. C. Stappers, Romain H. A. Toebosch, Emilia I. Barakova   +5 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Achieving circular economy at integrated waste treatment facility (tpst) in Banyumas: Mediating effect of women roles [PDF]

E3S Web of Conferences
The amount of waste in Indonesia continues to increase along with population growth. This high growth also contributes to waste generation, and one regency that initiates waste management is Banyumas.
Syauqi Nabhan Muhammad, Lestari Sofiana Tri, Romadlon Fauzan   +2 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source