Results 31 to 40 of about 2,934,302 (305)

INTGRT [PDF]

open access: yes, 2017
We are a non-profit organization with the goal to resettle refugees into a small-scale community with opportunities of education, employment, and housing.
Caldwell (Sustainability Design), Keaghan   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Concept of a human-centered electronic health record

open access: yesCurrent Directions in Biomedical Engineering
This paper examines the challenges and opportunities associated with the implementation of Electronic Health Records (EHR) globally and, specifically, in Germany. While EHRs promise improved accessibility and comprehensibility of patient data, healthcare
Remlinger Wolfram   +3 more
doaj   +1 more source

Solar Stove [PDF]

open access: yes, 2017
PEOPLE\u27S CHOICE AWARD WINNER! We designed a solar powered hot plate that also functions as a light source. This allows refugees to cook food without burning wood or using toxic fuels and provides a portable light source. Nexus Maximus IV The Challenge:
Beauchner (Industrial Design), Adam   +4 more
core   +1 more source

A multiobjective optimization framework for multicontaminant industrial water network design. [PDF]

open access: yes, 2011
The optimal design of multicontaminant industrial water networks according to several objectives is carried out in this paper. The general formulation of the water allocation problem (WAP) is given as a set of nonlinear equations with binary variables ...
Azzaro-Pantel, Catherine   +4 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Teaching Industrial Design Criticism [PDF]

open access: yes, 2001
This paper presents a methodology that allows students to learn criticism as a conceptual tool. Expertise is built up incrementally through the utilisation of lectures, seminars, debate and student presentations.
Blackler, Alethea
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Advancement and evaluation of a medical organization device

open access: yesCurrent Directions in Biomedical Engineering
In anaesthesia and intensive care medicine, managing the multitude of signal and substance lines connected to patients presents challenges, risking dislocations, incorrect treatment, and increased workload for healthcare professionals. Existing solutions
Langer Ferdinand   +5 more
doaj   +1 more source

Industrial Design: On Its Characteristics and Relationships to the Visual Fine Arts [PDF]

open access: yes, 1981
Industrial design and the visual arts share a common aesthetic basis as demonstrated by their common use of aesthetic principles and by designers who are also visual artists.
Carter, Curtis
core   +1 more source

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