Results 111 to 120 of about 5,423 (208)

Engineering Extracellular Vesicles: Strategies for Functional Modification and Clinical Translation

iNew Medicine, EarlyView.
The engineering modification strategies of extracellular vesicles (EVs). This figure presents the four core technical systems for the engineering modification of EVs, including direct modification strategies (physical and chemical methods), biological engineering methods, and hybrid and bionic strategies.
Zhouming Cheng, Wenhui Zhao, Min Wang, Xianwen Wang   +3 more
wiley   +1 more source

CRISPR-Cas9 Gene Editing in <i>Aspergillus</i>: From Pathogenesis to Metabolic Engineering. [PDF]

Biology (Basel)
Hu D, Zhao R, Lin Y, Jiang C.
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

A modular biodevice assembly tool kit for combinatorial screening and benchmarking multiple cell surface display platforms in Escherichia coli. [PDF]

J Biol Eng
Xu X, Choi IG.
europepmc   +1 more source

A Framework for Subgroup Dynamics Through the System Dynamics Lens: An Integrative Review of the Attribute and the Network Views

Journal of Organizational Behavior, EarlyView.
ABSTRACT Subgroups are dynamic entities evolving constantly in response to changing contexts and time. Although scholars from both the attribute and the network views have acknowledged that subgroups are inherently complex and fluid, research in these traditions has remained bifurcated, with limited efforts to integrate the two perspectives to more ...
Jinhee Moon, Chunghyun Oh, Chou‐Yu Tsai, Semin Park   +3 more
wiley   +1 more source

Expanding the Yeast MoClo Toolkit: gene expression control parts for <i>Saccharomyces cerevisiae</i> tested in industrially relevant conditions. [PDF]

Synth Biol (Oxf)
Blick E, Nygård Y.
europepmc   +1 more source

Reasoning BO: Enhancing Bayesian Optimization With the Reasoning Power of LLMs

Materials Genome Engineering Advances, EarlyView.
Addressing the challenge of too many parameters and too few experiments, reasoning BO enables AI‐accelerated scientific discovery. By searching smarter and reasoning deeper each round, this method achieves better results with fewer experiments than traditional approaches.
Zhuo Yang, Daolang Wang, Lingli Ge, Beilun Wang, Tianfan Fu, Yuqiang Li   +5 more
wiley   +1 more source

Random mutagenesis platform for accelerated genome evolution (RAMPAGE) of <i>Pichia pastoris</i>. [PDF]

Eng Microbiol
Pan Y, Gu X, Lv B, Dong C, Lian J.
europepmc   +1 more source

AlloyDesignClaw: Optimizing Castability and Mechanical Properties of Nickel‐Based Superalloys

Materials Genome Engineering Advances, EarlyView.
A stepwise optimization method is proposed for castability and mechanical properties of nickel‐based superalloys, enabling interpretable dimensionality reduction and efficient multi‐objective optimization of the composition space. An alloy design multi‐agent framework was further developed, integrating large language models, CALPHAD calculation ...
Jiaxuan Ma, Songyang Chen, Rui Feng, Xin Hao, Hang Zheng, Chushan Yi, Qingbiao Tan, Guoliang Zhu   +7 more
wiley   +1 more source

Evaluating the scientific and regulatory case for the deployment of the radioresistant genus <i>Deinococcus</i> in bioremediation. [PDF]

Front Microbiol
Vattikuti SS, Boren LS, Grosso RA, Albert CM, Hill JTE, Caro-Astorga J, Tuohy JM.   +6 more
europepmc   +1 more source