Results 41 to 50 of about 3,709,360 (283)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Gestão & Produção, 1994 Este trabalho trata da diagnose em equipamentos industriais através do uso de Sistemas Especialistas. Com o objetivo de desenvolver procedimentos que contribuam na construção de Sistemas Especialistas para diagnose em Manutenção Industrial, consideramos ...
Néocles Alves Pereira
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Foundation language models through the lens of manufacturing
Production and Manufacturing Research: An Open Access JournalAlthough recent studies have focused on foundation language models’ architectures, scaling properties, and applications in fields such as healthcare and business, no detailed investigation has addressed their role in manufacturing.
Sareh Aghaei, Fazel Ansari
doaj +1 more source
Systems integration in maintenance engineering [PDF]
, 2000 Integration in maintenance engineering systems provides a potential solution to some complex and conflicting problems. Decision making is often achieved with uncertainty and unknowns, while measuring against conflicting performance criteria.
Ball, Andrew +3 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Engineering ReportsMaintenance manuals are crucial information sources for maintenance and repair. Prior studies explored factual knowledge extraction from textual documents.
Zengkun Liu, Yuqian Lu
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Model Predictive collision-free path following control for nonholonomic mobile robots [PDF]
FME Transactions, 2023 In this research, a model predictive collision-free path following controller is developed and applied for an omnidirectional mobile robot (OMR). The mobile robot is controlled to track a reference path while avoiding collision with obstacles.
Hiep Thai Thanh +2 more
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