Results 51 to 60 of about 3,956,939 (297)

Leveraging Historical Breakdown Data for Enhanced Predictive and Prescriptive Maintenance Insights

Acta Technica Jaurinensis
The application of predictive and prescriptive maintenance procedures in industries is revolutionizing mainstream manufacturing by cutting down on time loss and waste of resources.
Amit Saxena
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Energy Efficiency Improvement of Diesel–Electric Trains Using Solar Energy: A Feasibility Study

Applied Sciences, 2022
Nowadays, productivity challenges in modern manufacturing systems have been the driving force in generating energy-efficient technologies in every industry, including diesel–electric locomotives.
Ahmad Fayad, Hussein Ibrahim, Adrian Ilinca, Sasan Sattarpanah Karganroudi, Mohamad Issa   +4 more
doaj   +1 more source

Towards Optimizing Multi-Level Selective Maintenance via Machine Learning Predictive Models

, 2023
The maintenance strategies commonly employed in industrial settings primarily rely on theoretical models that often overlook the actual operating conditions.
Amal Achour, Mohamed Ali Kammoun, Zied Hajej, Kammoun, Mohamed Ali, Hajej, Zied, Achour, Amal   +5 more
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Personalizing Industrial Maintenance Operation Using the Model of Hierarchical Complexity

Journal of Manufacturing and Materials Processing
The rapid advancement of Industry 4.0 technologies has transformed industrial maintenance operations, introducing digital work instructions as a critical tool for improving efficiency and reducing errors. However, existing digitalization approaches often
Gonçalo Raposo, Nuno Araújo, Marco Parente, António M. Lopes, Adriano Santos, Filipe Pereira, Sofia Leite, António Ramos Silva   +7 more
doaj   +1 more source

Energy Recovering Using Regenerative Braking in Diesel–Electric Passenger Trains: Economical and Technical Analysis of Fuel Savings and GHG Emission Reductions

Energies, 2021
Rail transport, specifically diesel–electric trains, faces fundamental challenges in reducing fuel consumption to improve financial performance and reduce GHG emissions.
Ahmad Fayad, Hussein Ibrahim, Adrian Ilinca, Sasan Sattarpanah Karganroudi, Mohamad Issa   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

An Event-Driven Dual-Mode Multilingual RAG Framework for Industrial Maintenance

IEEE Access
Industrial equipment fault diagnosis faces critical challenges in non-English operational environments. This paper presents an Event-Driven Dual-Mode Multilingual Retrieval-Augmented Generation (EDM-RAG) framework for industrial maintenance.
Ya-Jou Cheng, Shang-Liang Chen
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source