Results 51 to 60 of about 219,970 (306)
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior+5 more
wiley +1 more source
The study focuses on shipyards in north-east Italy (Trieste, Monfalcone, Venice are the interested areas) giving a tough view of the working conditions in the shipbuilding industry.
Enrico Bullian ha conseguito il titolo di Dottore di ricerca in Scienze Umanistiche, indirizzo storico e storico artistico presso l’Università degli Studi di Trieste. Ha già pubblicato monografie e saggi storici, in particolare sull’emergenza amianto. È docente in corsi sulla sicurezza sul lavoro nelle scuole secondarie ed è componente della Commissione Regionale Amianto. Svolge attività amministrativa negli enti locali della provincia di Gorizia.
doaj
Nanotechnology in medicine: European research and its implications
In this study, we explore and discuss nanoparticles and nanoscale materials and their use in medicine (nanomedicine) and pharmaceutics (nanopharmaceutics).
Margarethe Hofmann-Amtenbrink+3 more
doaj +1 more source
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley +1 more source
Pelatihan Dasar IoT Menggunakan Tinkercad Bagi Siswa SMK Kristen Immanuel Pontianak
Internet of Things (IoT) technology as one of the technologies in the Industrial Revolution 4.0 era allows communication between electronic devices and sensors via the internet. This is very helpful for human life.
Theresia Herlina Rochadiani+1 more
doaj +1 more source
Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu+6 more
wiley +1 more source
Background The aim of this study was to explore the relationships between teaching competence, career development, industrial orientation, and specialty construction in the case of intelligent medicine specialties in universities of traditional Chinese ...
Wei Lin+5 more
doaj +1 more source
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard+15 more
wiley +1 more source
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley +1 more source