Results 51 to 60 of about 5,311,545 (274)

SUATU PENDEKATAN BARU DALAM PRODUCT DEVELOPMENT COSTING UNTUK BARANG-BARANG INDUSTRI

Jurnal Akuntansi dan Keuangan, 1999
In the very competitive bussiness environment, the company ability to create or develop its product is an important thing to keep. With the competitivenes of each product, especially industrial product, each product has a short life-cycle. The life-cycle
Monika Kussetya Ciptani
doaj  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The Influence of Product Markets on Industrial Relations [PDF]

, 2006
Product markets are the foundation on which industrial relations institutions are built. Trade union strength is partly dependent upon the state of the labour market, but it is imperfections in the product market that are the precondition of their ...

core   +2 more sources

A metallic molybdenum dioxide with high stability for surface enhanced Raman spectroscopy

Nature Communications, 2017
Semiconducting materials are potential SERS substrates as alternatives to noble metals, but often suffer from poor stabilities and sensitivities. Here, the authors use molybdenum dioxide as a SERS material, showing high enhancement factors and stability ...
Qiqi Zhang, Xinshi Li, Qiang Ma, Qing Zhang, Hua Bai, Wencai Yi, Jingyao Liu, Jing Han, Guangcheng Xi   +8 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Per-Instance Algorithm Configuration in Homogeneous Instance Spaces: A Use Case in Reconfigurable Assembly Systems

Applied Sciences
The physical capabilities of a reconfigurable assembly system (RAS) increase the agility and responsiveness of the system in highly volatile market conditions.
Daniel Guzman Vargas, Sidharta Gautama, Mehmet Uzunosmanoglu, Birger Raa, Veronique Limère   +4 more
doaj   +1 more source

Design of Ergonomic Stool (Dingklik) for Batik Crafters

International Journal of Technology, 2014
Batik crafting is a job done in a sitting position. The design of a stool itself affects the sitting position of workers using it. This paper proposes an optimal design for batik stool (dingklik) which is tested using the task analysis toolkit in the ...
Shabila Anjani, Rachma Hidayati, Yoke A. Adlan, Amalia Suzianti, Radita T.V. Hapsari   +4 more
doaj   +1 more source