Results 31 to 40 of about 416,654 (265)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cellulose Nanofibers/Reduced Graphene Oxide Nanocomposites for Humidity Sensor
International Journal of Polymer ScienceCellulose nanofibers (CNFs) are part of organic crystallization macromolecular compounds that can be found in bacteria’s capsular polysaccharides and plant fibers.
Adib Bin Rashid +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
AHP BASED STARTUP BUSINESS SELECTION OF B2C TYPE E-BUSINESS - A CASE STUDY [PDF]
Management & Marketing, 2018 B2C, or business-to-consumer, is the type of commerce transaction in which businesses sell products or services to consumers. Small businesses are the most suitable for part-time or entrepreneurial experiences.
Limon SAHA +3 more
doaj
Energies, 2021 This study assesses the impact of economic and non-economic incentives to induce demand response in private households. The experiment was realized by a three-months residential phase in which two tenants lived in the Energy Smart Home Lab, an ...
Leandra Scharnhorst +3 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
A new formulation and solution for the nurse scheduling problem: A case study in Egypt
Alexandria Engineering Journal, 2018 Nurse Scheduling Problem (NSP) is the assignment of a number of nurses to a number of shifts in order to satisfy hospital’s demand. The objectives of NSP are the minimization of the overall hospital cost, and the maximization of nurses’ preferences while
Ahmed Ali El Adoly +2 more
doaj +1 more source
Clotrimazole for Treatment of Fungal Skin Infections Disease
Iraqi Journal of Industrial Research, 2023 The research includes the preparation of a pharmaceutical composition of Clotrimazole at a concentration of 2.5%, which is used to treat bacterial and fungal infections of the skin of field animals, which mainly work on ring worms, eczema (atopic ...
Ahmed J. Issa +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source