Results 41 to 50 of about 8,547,051 (298)

The Impact of Economic and Non-Economic Incentives to Induce Residential Demand Response—Findings from a Living Lab Experiment

Energies, 2021
This study assesses the impact of economic and non-economic incentives to induce demand response in private households. The experiment was realized by a three-months residential phase in which two tenants lived in the Energy Smart Home Lab, an ...
Leandra Scharnhorst, Thorben Sandmeier, Armin Ardone, Wolf Fichtner   +3 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Innovative Design and Scalable Manufacturing of a High-Performance Globe Valve with Plug-Type Disc [PDF]

JES: Journal of Engineering Sciences
This study presents the design and development of an advanced industrial-grade globe valve for enhanced flow control, excellent sealing performance, and augmented longevity.
Mohammad Musfeq Iqfath, Sakib Mahmud, Md Mahadi Hasan   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Clotrimazole for Treatment of Fungal Skin Infections Disease

Iraqi Journal of Industrial Research, 2023
The research includes the preparation of a pharmaceutical composition of Clotrimazole at a concentration of 2.5%, which is used to treat bacterial and fungal infections of the skin of field animals, which mainly work on ring worms, eczema (atopic ...
Ahmed J. Issa, Awatif I. Muhammed, Mahmud Mohamed, Rahim Jabar   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Hazard classification and risk prioritization in heavy manufacturing industries using natural language processing and MCDM method

Discover Artificial Intelligence
Heavy manufacturing industries are associated with different types of interacting hazards. Conventional identification and prioritization approaches are largely manual, subjective, and difficult to scale.
Rupok Islam Avi, Emonur Rahman Fahim, Md. Atiur Rahman, Shantonu Nonda, Md. Sanowar Hossain   +4 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Multi-objective design optimisation of a delta coordinate measurement machine [PDF]

MATEC Web of Conferences
A systematic approach for multi-objective optimisation in machine design is presented and further demonstrated through a case study on a delta Coordinate Measurement Machine (CMM).
Louw Jakobus Murray, de Ronde Willis, Marais Stephen, Maweni Thabisa   +3 more
doaj   +1 more source