Results 41 to 50 of about 3,012,398 (302)

A new formulation and solution for the nurse scheduling problem: A case study in Egypt

open access: yesAlexandria Engineering Journal, 2018
Nurse Scheduling Problem (NSP) is the assignment of a number of nurses to a number of shifts in order to satisfy hospital’s demand. The objectives of NSP are the minimization of the overall hospital cost, and the maximization of nurses’ preferences while
Ahmed Ali El Adoly   +2 more
doaj   +1 more source

Clotrimazole for Treatment of Fungal Skin Infections Disease

open access: yesIraqi Journal of Industrial Research, 2023
The research includes the preparation of a pharmaceutical composition of Clotrimazole at a concentration of 2.5%, which is used to treat bacterial and fungal infections of the skin of field animals, which mainly work on ring worms, eczema (atopic ...
Ahmed J. Issa   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Innovative Design and Scalable Manufacturing of a High-Performance Globe Valve with Plug-Type Disc [PDF]

open access: yesJES: Journal of Engineering Sciences
This study presents the design and development of an advanced industrial-grade globe valve for enhanced flow control, excellent sealing performance, and augmented longevity.
Mohammad Musfeq Iqfath   +2 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Multi-objective design optimisation of a delta coordinate measurement machine [PDF]

open access: yesMATEC Web of Conferences
A systematic approach for multi-objective optimisation in machine design is presented and further demonstrated through a case study on a delta Coordinate Measurement Machine (CMM).
Louw Jakobus Murray   +3 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

open access: yesAdvanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi   +3 more
wiley   +1 more source

Preparation of Sensitivity Test Antibiotic Discs Using Some Nanomaterials to Detect Resistance of Pseudomonas Aergenosa to Some Antibiotics

open access: yesIraqi Journal of Industrial Research, 2021
This study was conducted to synthesize bentonite nanoparticles and load them on different antibiotics to increase the effectiveness of the antibiotics or treat the resistance of Pseudomonas aeruginosa to some types of antibiotics in the laboratory.
Zainab J. Ghaneim   +5 more
doaj   +1 more source

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