Results 41 to 50 of about 1,413,007 (359)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Emergence of Digitalization and Artificial Intelligence in the Intellectual Property System

open access: yesInstitutiones Administrationis, 2023
This paper was set to address to what extent intellectual property law is prepared for keeping pace with the rapid development of artificial intelligence and digitalization?
Gábor Szilágyi, Judit Gyarmathy
doaj   +1 more source

Radiation properties of industrial waste

open access: yes, 2021
The problem of obtaining environmentally safe materials is especially important when using waste products that concentrate in themselves natural radionuclides (NR), which pose a danger to human health and the environment. Similar concentrators of NR include waste from the coal mining and power engineering industries.
Khobotova, E.B.   +3 more
openaire   +2 more sources

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

open access: yesFEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski   +13 more
wiley   +1 more source

Determinants of Industrial Property Rents in the Chicago Metropolitan Area [PDF]

open access: yes, 2016
Urban economists have long understood the theoretical importance of transportation infrastructure and accessibility on the location choice of households and firms.
Clark, David E.   +1 more
core   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

open access: yesFEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada   +3 more
wiley   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash   +6 more
wiley   +1 more source

Copyright as Property in the Post-Industrial Economy: A Research Agenda [PDF]

open access: yes, 2011
The incentives-for-authors formulation of copyright’s purpose is so deeply ingrained in our discourse and our thought processes that it is astonishingly hard to avoid invoking, even when one is consciously trying not to do so.
Cohen, Julie E.
core   +1 more source

Methods and Models of a Program Complex of Protection and Support of Subjects and Objects of the Industrial Property in the Internet/Intranet

open access: yesБезопасность информационных технологий, 2013
The basic methods and the models, the developed software of protection and active support in a network of subjects and objects of the industrial property (inventions and useful models) are considered.
Sergey Pavlovich Botuz   +3 more
doaj  

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