Results 101 to 110 of about 1,436,356 (295)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
CCarbon nanotubes, as carbon allotropes distinguished by their intricate structures and exceptional physicochemical properties, have demonstrated substantial progress in recent years across diverse domains, including energy production, chemical synthesis,
Zhizhi Tao +3 more
doaj +1 more source
Creative Industries Innovation Centre Case Study - Interaction Consortium.pdf
, 2015 In 2011, the Creative Industries Innovation Centre worked with its industry partners to select 50 high potential creative enterprises from around the nation to participate in a series of business model workshops.
Creative Industries Innovation Centre
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Prevalence of occupational injuries among workers in the iron and steel industries in Tanzania
Annals of Global HealthBackground: In Tanzania, iron and steel manufacturing industries are based on manual work with minor automation, as workers segregate scrap metals and add them to furnaces for melting.
Saumu Shabani +3 more
doaj +1 more source
Creative Industries Innovation Centre Case Study - The People's Republic of Animation.pdf
, 2015 PDF version of an article written for the Creative Industries Innovation Website creativeinnovation.net.au, part of a series of articles showcasing the experience and knowledge of companies in the creative industries in Australia.
Creative Industries Innovation Centre
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 1910 Two reports for 1909: "Sixth annual report of the Commissioner of Agriculture, Commerce and Industries" and "First annual report of the Commissioner of Agriculture, Commerce and Industries ...
South Carolina. Dept. of Agriculture, Commerce, and Industries.
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