Results 21 to 30 of about 541,036 (231)
TYPES OF INNOVATION AND ANALYSIS OF THEIR USAGE IN ECONOMY OF UZBEKISTAN
Вестник Российского экономического университета имени Г. В. Плеханова, 2019 The article shows different types of innovation and analyzes the number of technological, organizational and marketing innovation introduced in the Republic of Uzbekistan.
Nigora A. Ashurmetova +1 more
doaj +1 more source
Economic Situation for the Far-Eastern Federal istrict for 2005 [PDF]
Prostranstvennaâ Èkonomika, 2006 Based on current information for 2005, basic trends of the socio-economic development of the Far-Eastern Federal istrict have been evaluated. General economic situation, foreign trade, investment cooperation, situation in the social sphere have been ...
Elena Ibragimovna Devaeva +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk +9 more
wiley +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
PROBLEMS AND PROSPECTS OF DEVELOPMENT OF THE CONSTRUCTION INDUSTRY
Вестник Северо-Кавказского федерального университета, 2022 The article presents the analysis of the current state of the construction industry in the region, and also shows the evolution of the main indicators of its operation.
Alexander Kokorev, Vladimir Kuzmenko
doaj
Les jeux américains : une perspective historique
Sciences du Jeu, 2021 Little has been written in the United States about American boardgames and the way they reflect the evolution of the culture in which they were created during the short 140-year period.
Bruce Whitehill
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Atmosphere, 2022 This study was designed to assess the health impacts related to noninvasive carbon monoxide saturation (SPCO %) in the blood of respondents. For this purpose, 150 respondents from the labour community of Hattar Industrial Estate (testing site) and 100 ...
Suneela Jadoon +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source