Results 41 to 50 of about 1,436,356 (295)

التحليل الجغرافي للصناعات الصغيرة في مركز الزقازيق [PDF]

Maǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīd
قيام أي نشاط صناعي لابد له من مقومات طبيعية و بشرية, وجاء هذا البحث ليسلط الضوء على الصناعات الصغيرة في مركز الزقازيق، والتعرف علي توزيعها الجغرافي لمواقع الصناعات الصغيرة في مركز الزقازيق، كما ركز الباحث على بيان دور العوامل المؤثرة في الصناعات والتي ...
رأفت عثمان سلامة تمراز
doaj   +1 more source

A Systematic Analysis of how Practitioners Articulate Business Models across Disruptive Industries

Technology Innovation Management Review, 2020
Ongoing debates surround the role of business models in understanding the dynamics related to disruptive innovation. Too little is still known about how practitioners highlight different characteristics of business models across industries confronted ...
Alina Marie Herting, Alexander Lennart Schmidt   +1 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Iron ore development management in the Russian Federation

Управление
The Russian mineral resource complex is the basis for economy real sector development. The reserves of oil, gas, ferrous and non-ferrous metals, timber, and other raw materials are the strategic basis for the state economic development stability.
A. M. Belyaev, F. F. Sharipov, M. A. Dyakonova   +2 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

METODE PENDUGAAN KEMAMPUAN SUPPLY PRODUK KAYU DARI BERBAGAI INDUSTRI DI PROPINSI RIAU

Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
The aim of this investigation is to create a prediction model on the potentiality of supplying merchant wood products. The investigation was carried out in the province of Riau Four Sawmills and two plywood industries were selected for this study.
Han Roliadi, Buharman Buharman
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Creative Industries Innovation Centre Closure Q&A.pdf

, 2015
Information about the of the Creative Industries Innovation Centre in Q&A form, with information about creative business support services through the Entrepreneurs' Infrastructure Programme, final Biztro sessions, and a link to the Creative Industries ...
Creative Industries Innovation Centre
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source