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An Integrated PLS-SEM-TOPSIS-Sort Approach for Assessing ERP Solutions Acceptance Across Various Industries

open access: yesInformation
In the context of accelerated digitalization, enterprises are increasingly adopting information-driven solutions to support managerial decision-making, with Enterprise Resource Planning (ERP) systems playing a crucial role in organizational development ...
Aleksandra Radić   +4 more
doaj   +1 more source

التحليل الجغرافي للصناعات الصغيرة في مركز الزقازيق [PDF]

open access: yesMaǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīd
قيام أي نشاط صناعي لابد له من مقومات طبيعية و بشرية, وجاء هذا البحث ليسلط الضوء على الصناعات الصغيرة في مركز الزقازيق، والتعرف علي توزيعها الجغرافي لمواقع الصناعات الصغيرة في مركز الزقازيق، كما ركز الباحث على بيان دور العوامل المؤثرة في الصناعات والتي ...
رأفت عثمان سلامة تمراز
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

METODE PENDUGAAN KEMAMPUAN SUPPLY PRODUK KAYU DARI BERBAGAI INDUSTRI DI PROPINSI RIAU

open access: yesJurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017
The aim of this investigation is to create a prediction model on the potentiality of supplying merchant wood products. The investigation was carried out in the province of Riau Four Sawmills and two plywood industries were selected for this study.
Han Roliadi, Buharman Buharman
doaj   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Creative Industries Innovation Centre Closure Q&A.pdf

open access: yes, 2015
Information about the of the Creative Industries Innovation Centre in Q&A form, with information about creative business support services through the Entrepreneurs' Infrastructure Programme, final Biztro sessions, and a link to the Creative Industries ...
Creative Industries Innovation Centre
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

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