Results 21 to 30 of about 1,436,356 (295)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Economic Situation for the Far-Eastern Federal istrict for 2005 [PDF]
Пространственная экономика, 2006 Based on current information for 2005, basic trends of the socio-economic development of the Far-Eastern Federal istrict have been evaluated. General economic situation, foreign trade, investment cooperation, situation in the social sphere have been ...
Elena Ibragimovna Devaeva +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
TYPES OF INNOVATION AND ANALYSIS OF THEIR USAGE IN ECONOMY OF UZBEKISTAN
Вестник Российского экономического университета имени Г. В. Плеханова, 2019 The article shows different types of innovation and analyzes the number of technological, organizational and marketing innovation introduced in the Republic of Uzbekistan.
Nigora A. Ashurmetova +1 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Cogent Business & Management, 2022 Having an exchange rate close to its equilibrium is critical for foreign investors and policymakers during times of macroeconomic instability. This study measures the real exchange rate (RER) misalignment in eight Pakistani manufacturing industries from ...
Aqsa Shaukat +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
PROBLEMS AND PROSPECTS OF DEVELOPMENT OF THE CONSTRUCTION INDUSTRY
Вестник Северо-Кавказского федерального университета, 2022 The article presents the analysis of the current state of the construction industry in the region, and also shows the evolution of the main indicators of its operation.
Alexander Kokorev, Vladimir Kuzmenko
doaj
Les jeux américains : une perspective historique
Sciences du Jeu, 2021 Little has been written in the United States about American boardgames and the way they reflect the evolution of the culture in which they were created during the short 140-year period.
Bruce Whitehill
doaj +1 more source