Results 51 to 60 of about 2,972,702 (296)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
التحليل الجغرافي للصناعات الصغيرة في مركز الزقازيق [PDF]
Maǧallaẗ Kulliyyaẗ Al-ādāb Ǧāmiʿaẗ Būrsaʿīdقيام أي نشاط صناعي لابد له من مقومات طبيعية و بشرية, وجاء هذا البحث ليسلط الضوء على الصناعات الصغيرة في مركز الزقازيق، والتعرف علي توزيعها الجغرافي لمواقع الصناعات الصغيرة في مركز الزقازيق، كما ركز الباحث على بيان دور العوامل المؤثرة في الصناعات والتي ...
رأفت عثمان سلامة تمراز
doaj +1 more source
Case Summary: Teerapat Industries (Thailand) [PDF]
, 2008 WRC report on its investigation of labor violations at a Teerapat Industries factory in Thailand following complaints by concerned workers.
Worker Rights Consortium
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
InformationIn the context of accelerated digitalization, enterprises are increasingly adopting information-driven solutions to support managerial decision-making, with Enterprise Resource Planning (ERP) systems playing a crucial role in organizational development ...
Aleksandra Radić +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Does being R&D intensive still discourage outsourcing? : evidence from Dutch manufacturing [PDF]
, 2005 Being R&D intensive has traditionally been seen as an impediment to outsourcing. This study confirms that empirically this was the case for a set of manufacturing industries in the Netherlands in the early 1990s but also shows that R&D intensity became a
Mol, Michael J.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
METODE PENDUGAAN KEMAMPUAN SUPPLY PRODUK KAYU DARI BERBAGAI INDUSTRI DI PROPINSI RIAU
Jurnal Penelitian Hasil Hutan (Journal of Forest Products Research), 2017 The aim of this investigation is to create a prediction model on the potentiality of supplying merchant wood products. The investigation was carried out in the province of Riau Four Sawmills and two plywood industries were selected for this study.
Han Roliadi, Buharman Buharman
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source