Results 71 to 80 of about 1,467,776 (267)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

20140218 - Media Coverage of Valuing Australia's Creative Industries Report.pdf

open access: yes, 2015
An internal report of media coverage of the Valuing Australia's Creative Industries ...
Creative Industries Innovation Centre
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Alternatif Pengembangan Pendidikan Berdasarkan “Nilai” Kebutuhan Khusus

open access: yesHumaniora, 2015
The Community College is a kind of higher education. It focuses on diploma degree (the Two Year College). The objectives of Community College are to educate and to train students for getting working skills for jobs.
Silverius CJM Lake
doaj  

Integrating Artificial Intelligence into Service Innovation, Business Development, and Legal Compliance: Insights from the Hainan Free Trade Port Era

open access: yesSystems
This research aims to inspect the application of Artificial Intelligence (AI) in product and service innovation from the perspective of the Hainan Free Trade Port (HFTP) and its relationship with corporate transformation, legal compliance, and regulatory
Yincheng Li   +2 more
doaj   +1 more source

Creative Industries Innovation Centre Case Study - One Third.pdf

open access: yes, 2015
PDF version of an article written for the Creative Industries Innovation Website creativeinnovation.net.au, part of a series of articles showcasing the experience and knowledge of companies in the creative industries in Australia.
Creative Industries Innovation Centre
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Socio-Economic Effects of Orisumbare Sawmilling Industries on The Residents of Ikire, Irewole Local Government Area Osun-State, Nigeria

open access: yesCSID Journal of Infrastructure Development
The study examined the socio-economic effects of the Orisumbare sawmill industry on the residents of Ikire, Irewole local government area of Osun State.
Umar Usman Jimoh, D R. Ogungbemi
doaj   +1 more source

A modeling of internal effective factors over small and medium enterprises performance [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2015
: In response to bankruptcy of several small and medium enterprises(SMEs) in Mazandaran province, this research is conducted to identify the internal key factors that affect the performance of this enterprises.
Vali MOhamad Darini   +3 more
doaj  

Home - About - Disclaimer - Privacy