Results 21 to 30 of about 1,064,410 (251)

TECHNOLOGICAL STRUCTURE OF THE RUSSIAN INDUSTRY AND INDUSTRIAL REGIONS OF THE RUSSIAN FEDERATION

Векторы благополучия: экономика и социум, 2023
There is diversity in the Russian economy. Reducing the heterogeneity of the technological structure of industry is a complex issue. This determines the relevance of the study. The aim of the work is to clarify the technological structure of the domestic
Dmitry V. Sirotin
doaj   +1 more source

How Do We Learn about Drivers for Industrial Energy Efficiency—Current State of Knowledge

Energies, 2022
Drivers for industrial energy efficiency are factors that promote the sustained adoption of energy-efficient measures and practices. Leveraging drivers to overcome barriers and encourage action which improves industrial energy efficiency can contribute ...
Kelly M. Smith, Stephen Wilson, Paul Lant, Maureen E. Hassall   +3 more
doaj   +1 more source

Molecular Methods for Rare Hemoglobinopathy Cases: First Brazilian Report of Pediatric Siblings with Hb O‐Arab and Alpha‐Thalassemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hemoglobinopathies are prevalent globally; diagnosis is complex in high genetic admixture populations like Brazil. We report, in two pediatric siblings, the first documented cases in Brazil of heterozygosity for hemoglobin (Hb) O‐Arab with coinheritance of α‐thalassemia (αα/−α4.2; −α3.7/−α4.2), resulting in microcytic and hypochromic anemia ...
Elisângela de Souza Miranda Muynarsk, Amanda Cristina Meneguetti Berti, Bárbara Braga Vieira Marques, Victoria Simões Bernardo, Flaviene Felix Torres, Ingrid Souza Dias, Vanessa da Silveira Ramos de Castro, Gabriela Alves Bernardino, Danilo Grünig Humberto da Silva, Edis Belini‐Júnior   +9 more
wiley   +1 more source

A cost–benefit analysis for alcohol in South Africa for the year 2019

South African Journal of Economic and Management Sciences
Background: This article considers the impact of the production and consumption of alcohol on the economy of South Africa and on South Africa at large. It does this through estimating the costs of alcohol consumption for the South African (SA) society on
Graham Barr
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Socio-economic development of the Gorno-Badakhshan Autonomous Region

RUDN Journal of Economics, 2022
Gorno-Badakhshan Autonomous Region (GBAO) occupies the entire eastern part of Tajikistan, being the largest region of the country in terms of area. Almost the entire territory of GBAO is occupied by highlands, where the Pamir highland system is located ...
Farzona M. Garibova
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

TÜRKİYE'DEKİ TEKNOPARKLARDA KADIN İSTİHDAMI

Mehmet Akif Ersoy Üniversitesi İktisadi ve İdari Bilimler Fakültesi Dergisi, 2017
Kadın geçmişten günümüze daima çalışma hayatının önemli dinamiklerinden biri olmuştur. Kadının çalışma hayatındaki rolü, çalışma ilişkilerinde ortaya çıkan yapısal değişimlerden büyük ölçüde etkilenmiştir.
Gökçe Cerev, Fatih Savuk, Hasan Uzun
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source