Results 31 to 40 of about 674,800 (303)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Ontology Building of Manufacturing Quality Knowledge for Design Decision Support [PDF]

open access: yes, 2010
This work was funded by National Natural Science Foundation of China (No: 70472066, 70771091), the project of Bureau of Science, Technology and Industry for National Defence, China (No. Z142008A001), the NPU Foundation for Humanities, Social Science, and
EYNARD, Benoit   +4 more
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

An Automatic Generation Method of Finite Element Model Based on BIM and Ontology

open access: yesBuildings, 2022
For the mechanical analysis work in the structural design phase, data conversion and information transfer between BIM model and finite element model have become the main factors limiting its efficiency and quality, with the development of BIM (building ...
Jing Jia   +5 more
doaj   +1 more source

IFC-based calculation of the Flemish Energy Performance Standard [PDF]

open access: yes, 2009
This paper illustrates our findings concerning space based design methodologies and interoperability issues for today's Building Information Modeling (BIM) environments.
De Meyer, Ronald   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Validation of Support for Creation of License Drawings Using Application for openBIM-Based Automatic Generation of 2D Drawings

open access: yesApplied Sciences, 2020
In the preparation of drawings and documents required for a licensing process, the main problem is the duplication of work in creating design drawings and Building Information Modeling (BIM) models. To overcome this problem, BIM authoring tools provide a
Inhan Kim   +4 more
doaj   +1 more source

Creating information delivery specifications using linked data [PDF]

open access: yes, 2019
The use of Building Information Management (BIM) has become mainstream in many countries. Exchanging data in open standards like the Industry Foundation Classes (IFC) is seen as the only workable solution for collaboration.
Pauwels, Pieter   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An Automated IoT Visualization BIM Platform for Decision Support in Facilities Management

open access: yesApplied Sciences, 2018
Building information modeling (BIM) is the digital representation of physical and functional characteristics (such as geometry, spatial relationship, and geographic information) of a facility to support decisions during its life cycle.
Kai-Ming Chang, Ren-Jye Dzeng, Yi-Ju Wu
doaj   +1 more source

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