Results 81 to 90 of about 148,995,678 (263)

Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain. [PDF]

, 2011
Recent discovery of 5-hydroxymethylcytosine (5hmC) in genomic DNA raises the question how this sixth base is recognized by cellular proteins. In contrast to the methyl-CpG binding domain (MBD) of MeCP2, we found that the SRA domain of Uhrf1, an essential
Frauer, C., M. Cristina Cardoso, Leonhardt, Heinrich, Frauer, Carina, Bultmann, Sebastian, Casa, V., Valentina Casa, Frauer Carina, Hoffmann, T., Cardoso, M. Cristina, Leonhardt Heinrich, Antes, I., Casa Valentina, Iris Antes, Leonhart, H., Heinrich Leonhardt, Cardoso M. Cristina, Hoffmann Thomas, Hoffmann, Thomas, Antes Iris, Thomas Hoffmann, M Cristina Cardoso, Bultmann Sebastian, Bultmann, S., Antes, Iris, Casa, Valentina, Carina Frauer, Sebastian Bultmann   +27 more
core   +2 more sources

Hidden in the Labour Market: An Intersectional Latent Class Analysis of Discouraged Workers in Australia

Australian Journal of Social Issues, EarlyView.
ABSTRACT This study employs an intersectionality‐informed latent class analysis (LCA) to examine the hidden diversity of discouraged workers in Australia. Drawing on nationally representative data from the Household, Income and Labour Dynamics in Australia Survey, we identified six empirically distinct subgroups defined by intersecting demographic and ...
Sora Lee, Woojin Kang
wiley   +1 more source

hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity [PDF]

, 2011
hSSB1 is a recently discovered single-stranded DNA binding protein that is essential for efficient repair of DNA double-strand breaks (DSBs) by the homologous recombination pathway.
Dinoop Menon, Cubeddu, Liza (R16726), Bain, Amanda, White, Malcolm F., Emma Bolderson, Urquhart, Aaron J., Aaron J. Urquhart, Bolderson, Emma, Khanna, Kum Kum, Menon, Dinoop, Derek J. Richard, Amanda Bain, Malcolm F. White, Richard, Derek J., Kum Kum Khanna, Liza Cubeddu, Cubeddu, Liza   +16 more
core   +2 more sources

Strengthening Treaty Understanding: The Role of Education in Building Durable Indigenous–State Agreements

Australian Journal of Social Issues, EarlyView.
ABSTRACT Education is a central mechanism for ensuring that Indigenous–State treaties are understood, supported and endure through political change. Public knowledge shapes the negotiation, acceptance, implementation and long‐term stability of agreements. In Australia, however, treaty knowledge remains fragmented.
Jacob Prehn, Harry Hobbs, Jessica Horton
wiley   +1 more source

Reducing health inequalities through general practice: a realist review and action framework

Health and Social Care Delivery Research
Background Socio-economic inequalities in health have been in the public agenda for decades. General practice has an influential role to play in mitigating the impact of inequalities especially regarding chronic conditions.
Anna Gkiouleka, Geoff Wong, Sarah Sowden, Isla Kuhn, Annie Moseley, Sukaina Manji, Rebecca R Harmston, Rikke Siersbaek, Clare Bambra, John A Ford   +9 more
doaj   +1 more source

A fRAmework of the DetermInants of Arts aNd Cultural Engagement (RADIANCE): integrated insights from ecological, behavioural and complex adaptive systems theories [version 1; peer review: 2 approved]

Wellcome Open Research
Background Arts and cultural engagement (ACEng) is ubiquitous across every human culture since palaeolithic times, but in contemporary society, ACEng is unevenly distributed, demographically, socio-economically, geographically and politically.
Daisy Fancourt, Katey Warran
doaj   +1 more source

Artificial Intelligence and Access to Justice at the ‘Shop Front’: The Potential and Limitations of Meeting Legal Need Through Technology

Australian Journal of Social Issues, EarlyView.
ABSTRACT In Australia, governments fund Community Legal Centres (CLCs) as part of the legal assistance sector (LAS) to meet the ‘legal needs’ of people experiencing disadvantage who cannot afford private legal services. Persistent unmet demand for CLCs is well‐documented. As artificial intelligence (AI) is increasingly used in private legal practice to
Catherine Hastings, Art Cotterell, Farzana Bruce   +2 more
wiley   +1 more source

Monitoring of trends in socioeconomic inequalities in mortality [PDF]

This paper presents estimates of changes in socioeconomic inequalities in mortality between the 1980s and the 1990s in nine European countries. The best available evidence shows that relative inequalities in mortality generally widened, while the ...
FFF2Paula NNN2Santana, FFF2Otto NNN2Andersen, FFF2Vivian NNN2Bos, FFF2Seeromanie NNN2Harding, FFF2Mario NNN2Cardano, FFF2Örjan NNN2Hemström, FFF2Johan P. NNN2Mackenbach, FFF2Giuseppe NNN2Costa, FFF2Richard NNN2Layte, FFF2Alison NNN2Reid, FFF2Tapani NNN2Valkonen, FFF2Enrique NNN2Regidor, FFF1Anton E. NNN1Kunst   +12 more
core  

The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines [PDF]

, 2014
The hexameric MCM complex is the catalytic core of the replicative helicase in eukaryotic and archaeal cells. Here we describe the first in vivo analysis of archaeal MCM protein structure and function relationships using the genetically tractable ...
Tatjana P Kristensen, Reeja Maria Cherian, Reeja eMaria Cherian, Stuart A MacNeill, MacNeill, Stuart, Kristensen, Tatjana P., Fiona C Gray, Gray, Fiona C., Fiona C. Gray, Tatjana P. Kristensen, Stuart A. MacNeill, Cherian, Reeja Maria, Macneill, Stuart Andrew   +12 more
core   +1 more source

Carspecken's critical ethnography method in qualitative nursing research: An approach to address health inequalities [PDF]

Nursing and Midwifery Studies
The domain of nursing care is inherently complex and multifaceted, characterized by continuous evolution, diverse stakeholders, and intricate systems influenced by numerous factors.
Reza Abdollahi
doaj   +1 more source