Results 151 to 160 of about 99,752 (238)

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Toxicity of respirable coal dust: An overview of origin, chemistry, mechanisms, and possible remedies. [PDF]

Int J Coal Sci Technol
Eskanlou A, Arnold BJ.
europepmc   +1 more source

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

Activated Charcoal: A Highly Potent Legal Alternative for <i>Vespa velutina</i> Nest Destruction. [PDF]

Insects
Presuhn AWM, Ernst UR.
europepmc   +1 more source

A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles. [PDF]

Crit Rev Toxicol, 2023
Lam CW, Castranova V, Driscoll K, Warheit D, Ryder V, Zhang Y, Zeidler-Erdely P, Hunter R, Scully R, Wallace W, James J, Crucian B, Nelman M, McCluskey R, Gardner D, Renne R, McClellan R.   +16 more
europepmc   +1 more source

Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair

Advanced Science, EarlyView.
Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou, Fan Zhang, Jiangbo Wang, Huiyuan Wang, Zongqiang Wang, Qianqian Wang, Chuikai Meng, Jialu Sun, Han Wang, Weiye Li, Ziyi Zhao, Le Qi, Xiaosong Gu, Shusen Cui, Rangjuan Cao   +14 more
wiley   +1 more source

A Scalable Double‐Sided Wet Etching Strategy for Large‐Area Mushroom‐Shaped Bionic Adhesives

Advanced Science, EarlyView.
This work presents a scalable manufacturing strategy for high‐performance, large‐area, mushroom‐shaped bio‐inspired adhesives. Using a double‐sided wet etching process, the complex 3D metal molds are fabricated rapidly and controllably. The resulting adhesive structures exhibit strong, stable adhesion under various conditions, including atmosphere and ...
Keju Ji, Xinran Xu, Jian Chen, Wenjie Chen, Xiaolei Zhu, Haixiang Ma, Xingyu Jiang, Changhong Linghu, Zhendong Dai   +8 more
wiley   +1 more source

Evaluation of two new insecticide formulations based on inert dusts and botanicals against four stored-grain beetles

Julius-Kühn-Archiv, 2018
Korunic, Zlatko O., Fields, Paul G.
doaj   +1 more source

Corundum Aggregates With Microplastics Revealed by Raman Scattering and Fluorescence Study of Children's Urine in Hospital Environment. [PDF]

J Biophotonics
Voronine DV, Nourachi B, Dao T, Gutierrez HR, Heromin R, DeRosa J, Ford A, Bruzek S, Ignjatovic V, Schleif W, Snyder CW.   +10 more
europepmc   +1 more source

Post-Harvest Insect Pests and Their Management Practices for Major Food and Export Crops in East Africa: An Ethiopian Case Study. [PDF]

Insects, 2022
Berhe M, Subramanyam B, Chichaybelu M, Demissie G, Abay F, Harvey J.   +5 more
europepmc   +1 more source