Results 121 to 130 of about 624,295 (329)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Quantitative Difference Between the Effective Inertia and Set Inertia Parameter of Virtual Synchronous Generators

Energies
Virtual synchronous generators (VSGs) have been developed to mitigate the increase in the rate of change of frequency (ROCOF) in power systems by replacing synchronous generators (SGs) with inverter-based resources. VSGs mimic the dynamics and control of
Ryosuke Shikuma, Dai Orihara, Hiroshi Kikusato, Akihisa Kaneko, Hisao Taoka, Yasuhiro Hayashi   +5 more
doaj   +1 more source

Technical and Economic Impact of the Inertia Constraints on Power Plant Unit Commitment

, 2020
Carmelo Mosca, Ettore Bompard, Gianfranco Chicco, Benedetto Aluisio, Michela Migliori, Chiara Vergine, Paolo Cuccia   +6 more
openalex   +1 more source

Effect of yaw moment of inertia on vehicle transient behaviour to steer

, 2022
Hideki Sakai
openalex   +2 more sources

Improved Grey Wolf Optimization Algorithm Based on Hyperbolic Tangent Inertia Weight [PDF]

, 2023
Weiming Lin
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Sources of inertia in an expanding universe

Open Physics, 2015
In a cosmological perspective, gravitational induction is explored as a source to mechanical inertia in line with Mach’s principle. Within the standard model of cosmos, considering the expansion of the universe and the necessity of retarded interactions,
Prytz Kjell
doaj   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source