Results 61 to 70 of about 216,322 (317)

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Improving Tools for the Analysis of Brain Based Measures of Infant Information Processing [PDF]

, 2012
While current methodological approaches to data-acquisition and -analysis used in ERP-studies have shown to be appropriate for adult populations, their applicability with infant populations is debatable.
STETS, MANUELA
core  

Neonatal resuscitation and immediate newborn assessment and stimulation for the prevention of neonatal deaths: a systematic review, meta-analysis and Delphi estimation of mortality effect. [PDF]

, 2011
BACKGROUND: Of 136 million babies born annually, around 10 million require assistance to breathe. Each year 814,000 neonatal deaths result from intrapartum-related events in term babies (previously "birth asphyxia") and 1.03 million from complications of
Carlo, Waldemar A, Bhutta Zulfiqar A, Darmstadt Gary L, Zulfiqar A Bhutta, Lawn, Joy E, Stephen N Wall, Gary L Darmstadt, Gill Christopher, Wall, Stephen N, Lawn, Joy E., Wall, Stephen N., Lawn Joy E, Joy E Lawn, Darmstadt, Gary L, Niermeyer Susan, Cousens Simon, Simon Cousens, William J Keenan, Lee, Anne CC, Gill, Christopher, Bhutta, Zulfiqar Ahmed, Lee Anne CC, Keenan, William J., Cousens, Simon, Susan Niermeyer, Keenan William J, Darmstadt, Gary L., Wall Stephen N, Bhutta, Zulfiqar A, Keenan, William J, Christopher Gill, Carlo, Waldemar A., Anne CC Lee, Carlo Waldemar A, Niermeyer, Susan, Lee, Anne C. C., Waldemar A Carlo   +36 more
core   +1 more source

Salmonella enterica Serovars Typhi and Paratyphi A are avirulent in newborn and infant mice even when expressing virulence plasmid genes of Salmonella Typhimurium

Journal of Infection in Developing Countries, 2010
Background: Salmonella enterica serovars Typhi and Paratyphi A are human host-restricted pathogens. Therefore, there is no small susceptible animal host that can be used to assess the virulence and safety of vaccine strains derived from these Salmonella
Javier Santander, Roy Curtiss III
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Neuroprotection in the Newborn Infant [PDF]

Clinics in Perinatology, 2009
Neonatal brain injury is an important cause of death and disability, with pathways of oxidant stress, inflammation, and excitotoxicity that lead to damage that progresses over a long period of time. Therapies have classically targeted individual pathways during early phases of injury, but more recent therapies such as growth factors may also enhance ...
Fernando F, Gonzalez, Donna M, Ferriero
openaire   +2 more sources

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

Arthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah, Swaleh Hussain, Sara J. T. Guilcher, Lisa M. McCarthy, Dharini Mahendira, Howard Berger, Mina Tadrous   +6 more
wiley   +1 more source

Engineered Heparinized GQDS/HPEI–Polyamide Membrane for Bilirubin Removal via One Step Anti Coagulation

Advanced Materials Interfaces, EarlyView.
A multifunctional heparinized polyamide membrane embedded with graphene quantum dots (GQDs) and hyperbranched polyethyleneimine (HPEI) is engineered for efficient bilirubin removal via a one‐step anticoagulation–adsorption process. The membrane demonstrates enhanced hemocompatibility, prolonged clotting times, and high bilirubin adsorption capacity ...
Abdur Rehman Mushtaq Ahmad, Maria Wasim, Aneela Sabir, Muhammad Shafiq, Syed Abdul Basit Shah, Maoz Maoz, Vanni Lughi   +6 more
wiley   +1 more source

The effect of maternal common mental disorders on infant undernutrition in Butajira, Ethiopia: the P-MaMiE study. [PDF]

, 2010
BACKGROUND: Although maternal common mental disorder (CMD) appears to be a risk factor for infant undernutrition in South Asian countries, the position in sub-Saharan Africa (SSA) is unclear METHODS: A population-based cohort of 1065 women, in the third ...
Mark Tomlinson, Vikram Patel, Prince Martin, Atalay Alem, Fikru Tesfaye, Mesfin Aray, Worku Bogale, Tomlinson Mark, Abdulahi, Abdulreshid, Abdulahi Abdulreshid, Medhin, Girmay, Zufan Lakew, Abdulreshid Abdulahi, Marcus Hughes, Lakew Zufan, Charlotte Hanlon, Bogale Worku, Worku, Bogale, Alem, Atalay,, Hughes Marcus, Martin Prince, Prince, Martin, Lakew, Zufan, Hanlon Charlotte, Aray, Mesfin, Dewey Michael, Michael Dewey, Alem Atalay, Tesfaye, Fikru, Patel Vikram, Dewey, Michael, Alem, Atalay, Aray Mesfin, Patel, Vikram, Hanlon, Charlotte, Tesfaye Fikru, Hughes, Marcus, Girmay Medhin, Medhin Girmay, Tomlinson, Mark   +39 more
core   +1 more source